Utility of a Urine Screening Tool for Vitamin D Deficiency in Infants and Toddlers

Launched by NEMOURS CHILDREN'S CLINIC · Apr 15, 2010

Keywords

ClinConnect Summary

Background:

Insufficient circulating levels of vitamin D is a common problem in both developed and developing countries; it is estimated that over one billion people have vitamin D deficiency at this time. In children, vitamin D deficiency leads to nutritional rickets, which is considered the most common non-communicable disease of children worldwide. Rickets causes significant short term morbidity and mortality through hypocalcemic tetany and seizures, as well as long term morbidity from growth delay and skeletal deformities. Recent data also suggest that children who have had nutritional...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • In one of the 6 high-risk groups between the age of 6 months and 3 years.
• Exclusion Criteria:
• • known familial rickets (hypophosphatemic or vitamin D resistant)
• • known parathyroid hormone problems
• • any child on diuretics
• • presence of a chronic disease or use of medications known to affect vitamin D metabolism
• • renal insufficiency
• • known malabsorption
• • rickets secondary to other syndromes (e.g. Fanconi syndrome)