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Search / Trial NCT01139671

Comparison of Sufentanil and Remifentanil Infusion During General Anaesthesia for Removal of Wisdom Teeth in Ambulatory Surgery

Launched by UNIVERSITY HOSPITAL, CLERMONT-FERRAND · Jun 7, 2010

Trial Information

Current as of June 12, 2025

Completed

Keywords

Remifentanil Sufentanil Surgical Removal Of Three To Four Wisdom Teeth General Anaesthesia Ambulatory Oral Surgery Target Controlled Infusion (Tci) Opioid Induced Hyperalgesia Postoperative Nausea And Vomiting Postoperative Morphine Consumption Under General Anaesthesia In Ambulatory Surgery

ClinConnect Summary

Patients will be enrolled during the preoperative anaesthetic assessment. Premedication will be achieved with oral administration of hydroxyzine 1 mg/kg the morning before surgery.

The induction of general anaesthesia will be achieved using TARGET CONTROLLED INFUSION (TCI) of propofol associated to TCI of remifentanil or sufentanil, depending on randomization.

The conditions of endotracheal intubation will be evaluated by the Percentage Of Glottic Opening Score (POGO) and the Cormack and Lehane Score.

Mechanical volume-controled ventilation will aim to maintain normocapnia. The baseline ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • -age between 15 and 35 years old
  • American Society of Anaesthesiologists (ASA) physical status I or II
  • Surgical removal of three to four wisdom teeth
  • general anaesthesia
  • Ambulatory surgery
  • Exclusion Criteria:
  • Obesity (Body mass index \> 30 kg.m-²)
  • Pregnancy
  • Contraindication for nitrous oxide inhalation
  • Patient refusal

About University Hospital, Clermont Ferrand

The University Hospital of Clermont-Ferrand is a leading academic medical institution dedicated to advancing healthcare through innovative research and clinical trials. Renowned for its multidisciplinary approach, the hospital integrates cutting-edge scientific inquiry with patient care, fostering an environment that promotes collaboration among healthcare professionals, researchers, and academic partners. With a strong commitment to improving patient outcomes, the institution actively engages in a wide array of clinical studies, ranging from early-phase trials to large-scale interventions, aimed at addressing critical health challenges and enhancing treatment modalities. Its state-of-the-art facilities and expertise make it a pivotal contributor to clinical research in the region and beyond.

Locations

Clermont Ferrand, , France

Patients applied

0 patients applied

Trial Officials

Sophie Gonnu-Levallois

Principal Investigator

University Hospital, Clermont-Ferrand

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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