Fruit And Vegetables and OUtcomes After Removal of Impacted TEeth

Launched by UNIVERSITY OF BIRMINGHAM · Jun 16, 2010

Keywords

ClinConnect Summary

In general antioxidant status appears to influence wound healing in humans and in animal models of acute trauma, with low antioxidant concentrations and excessive oxidative stress being associated with impaired healing. Whilst antioxidant supplementation has been reported to improve plasma antioxidant status and wound healing in animal models of acute trauma, there is remarkably little data from human studies.

The use of Juice Plus+ has been reported to increase serum concentrations of important antioxidants and reduce serum markers of oxidative stress. However, to date there are no report...

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Eligibility criteria

• Inclusion Criteria:
• • 1. Patient requiring surgical removal of a single (unilateral) mandibular wisdom tooth
• • 2. Tooth requiring full mucoperiosteal flap to be raised for removal
• • 3. Bone removal necessary during procedure.
• Exclusion Criteria:
• • 1. Patients refusing to give written informed consent
• • 2. Clinically significant or unstable physical or mental disability rendering the participants incapable of complying with the study protocol as judged by the investigator
• • 3. Pregnant or breast-feeding women
• • 4. Patients taking long term anti-microbial or anti-inflammatory drugs
• • 5. Patients unable to swallow Juice Plus capsules
• • 6. Patients taking regular vitamin or mineral supplementation
• • 7. Patients requiring pre-operative antibiotics for surgery
• • 8. Patients requiring concomitant extractions or contralateral lower 3rd molar removal
• • 9. Allergic to any of the ingredients contained in supplements or placebo medication.