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Search / Trial NCT01156883

Combination Chemotherapy in Treating Young Adult Patients With Acute Lymphoblastic Leukemia

Launched by GRUPPO ITALIANO MALATTIE EMATOLOGICHE DELL'ADULTO · Jul 2, 2010

Trial Information

Current as of May 10, 2025

Completed

Keywords

B Cell Adult Acute Lymphoblastic Leukemia Recurrent Adult Acute Lymphoblastic Leukemia T Cell Adult Acute Lymphoblastic Leukemia Untreated Adult Acute Lymphoblastic Leukemia

ClinConnect Summary

OBJECTIVES:

* To determine the feasibility of combination chemotherapy in young adult patients with acute lymphoid leukemia.
* To determine the complete response rate at the end of induction therapy in these patients.
* To determine the overall survival of patients treated with these regimens.
* To determine the disease-free survival of patients treated with these regimens.
* To determine the event-free survival of patients treated with these regimens.
* To determine toxicity of these regimens.
* To determine compliance related to dose intensity.

OUTLINE:

* Steroids prephase therapy: All...

Gender

ALL

Eligibility criteria

  • DISEASE CHARACTERISTICS:
  • * Diagnosis of acute lymphoid leukemia, meeting any of the following criteria:
  • Non-mature B-cell disease
  • Non-Philadelphia chromosome positive disease
  • T -cell or B-cell phenotype
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • Prior pretreatment with antiblastic chemotherapy allowed

About Gruppo Italiano Malattie Ematologiche Dell'adulto

The Gruppo Italiano Malattie Ematologiche dell'Adulto (GIMEMA) is a prestigious Italian research group dedicated to advancing the understanding and treatment of adult hematological diseases. Comprising a network of leading hematologists and clinical researchers, GIMEMA conducts innovative clinical trials aimed at improving patient outcomes through the development of novel therapeutic strategies and evidence-based practices. With a strong emphasis on collaboration and scientific rigor, GIMEMA plays a pivotal role in enhancing the landscape of hematology both in Italy and internationally, contributing significantly to the global body of research and clinical knowledge in this critical field.

Locations

Rome, , Italy

Udine, , Italy

Ancona, , Italy

Avellino, , Italy

Bologna, , Italy

Brindisi, , Italy

Catania, , Italy

Milano, , Italy

Palermo, , Italy

Pescara, , Italy

Roma, , Italy

Roma, , Italy

Roma, , Italy

Roma, , Italy

Verona, , Italy

Genova, , Italy

Napoli, , Italy

Reggio Calabria, , Italy

Sassari, , Italy

Ascoli Piceno, , Italy

Nocera Inferiore, , Italy

Lecce, , Italy

Novara, , Italy

San Giovanni Rotondo, , Italy

Arezzo, , Italy

Catanzaro, , Italy

Modena, , Italy

Parma, , Italy

Roma, , Italy

Ferrara, , Italy

Palermo, , Italy

Roma, , Italy

Bari, , Italy

Ravenna, , Italy

Reggio Emilia, , Italy

Messina, , Italy

Pavia, , Italy

Roma, (Rm), Italy

Napoli, , Italy

Napoli, , Italy

Pisa, , Italy

Roma, , Italy

Trani, , Italy

Patients applied

0 patients applied

Trial Officials

Roberto Foa, MD

Principal Investigator

Universita Degli Studi "La Sapeinza"

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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