Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results
Launched by NOVO NORDISK A/S · Aug 9, 2010
Trial Information
Current as of April 24, 2025
Completed
Keywords
ClinConnect Summary
No description provided
Gender
ALL
Eligibility criteria
- • Inclusion Criteria: - Type 2 diabetes - Age min. 50 years at screening and concomitant cardiovascular, cerebrovascular or peripheral vascular disease or chronic renal failure or chronic heart failure OR age min. 60 years at screening and other specified risk factors of cardiovascular disease - HbA1c: 7.0% or above - Anti-diabetic drug naive or treated with one or more oral anti-diabetic drugs (OADs) or treated with human NPH insulin or long-acting insulin analogue or premixed insulin, alone or in combination with OAD(s) Exclusion Criteria: - Type 1 diabetes - Use of a glucagon-like peptide-1 (GLP-1) receptor agonist (exenatide, liraglutide or other) or pramlintide or any dipeptidyl peptidase 4 (DPP-4) inhibitor within the 3 months prior to screening (trial start) - Use of insulin other than human NPH insulin or long-acting insulin analogue or premixed insulin within 3 months prior to screening. Short-term use of other insulin during this period in connection with intercurrent illness is allowed, at Investigator's discretion
Trial Officials
Global Clinical Registry (GCR, 1452)
Study Director
Novo Nordisk A/S
About Novo Nordisk A/S
Novo Nordisk A/S is a global healthcare company headquartered in Denmark, specializing in the research, development, manufacturing, and marketing of innovative pharmaceuticals, particularly in the fields of diabetes care, obesity treatment, and hormone replacement therapies. With a strong commitment to improving patient outcomes, Novo Nordisk invests significantly in clinical trials to advance scientific knowledge and develop effective therapies. The company is dedicated to sustainability and ethical practices, striving to deliver high-quality healthcare solutions while addressing the evolving needs of patients worldwide. Through collaboration and innovation, Novo Nordisk aims to lead the way in transforming diabetes and other chronic diseases into manageable conditions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Miami, Florida, United States
Minneapolis, Minnesota, United States
Albany, New York, United States
Philadelphia, Pennsylvania, United States
Columbia, South Carolina, United States
Greer, South Carolina, United States
Anaheim, California, United States
Chicago, Illinois, United States
Kuopio, , Finland
örebro, , Sweden
Bristol, , United Kingdom
Dundee, , United Kingdom
Orlando, Florida, United States
Stavanger, , Norway
Newark, Delaware, United States
Greenville, North Carolina, United States
Arlington, Texas, United States
Baltimore, Maryland, United States
Syracuse, New York, United States
Dallas, Texas, United States
Denver, Colorado, United States
Esbjerg, , Denmark
Hvidovre, , Denmark
Corbeil Essonnes, , France
Etten Leur, , Netherlands
Palma De Mallorca, , Spain
Asheville, North Carolina, United States
Toronto, Ontario, Canada
New Orleans, Louisiana, United States
Mobile, Alabama, United States
West Palm Beach, Florida, United States
Haifa, , Israel
Taoyuan, , Taiwan
Birmingham, Alabama, United States
Louisville, Kentucky, United States
New York, New York, United States
Memphis, Tennessee, United States
Graz, , Austria
Aalborg, , Denmark
Paris, , France
Leipzig, , Germany
Tel Hashomer, , Israel
Amsterdam, , Netherlands
Utrecht, , Netherlands
Barcelona, , Spain
Madrid, , Spain
århus C, , Denmark
Nimes, , France
Bologna, , Italy
Milano, , Italy
Ulm, , Germany
Guangzhou, Guangdong, China
Shanghai, Shanghai, China
Gent, , Belgium
Liège, , Belgium
Odense, , Denmark
Dresden, , Germany
Firenze, , Italy
Lucca, , Italy
Roma, , Italy
Hoogeveen, , Netherlands
Moscow, , Russian Federation
Mostoles Madrid , , Spain
Bursa, , Turkey
Aberdeen, , United Kingdom
Birmingham, , United Kingdom
Edinburgh, , United Kingdom
Guildford, , United Kingdom
Torquay, , United Kingdom
Coventry, , United Kingdom
Swansea, , United Kingdom
Hobart, Tasmania, Australia
Vellore, Tamil Nadu, India
Bucharest, , Romania
Göteborg, , Sweden
Leuven, , Belgium
Jerusalem, , Israel
Oslo, , Norway
Cape Town, Western Cape, South Africa
Cleveland, Ohio, United States
Nizhniy Novgorod, , Russian Federation
Wien, , Austria
Edegem, , Belgium
Ludwigshafen, , Germany
Escondido, California, United States
Walnut Creek, California, United States
Oklahoma City, Oklahoma, United States
Durban, Kwazulu Natal, South Africa
Malmö, , Sweden
Lahti, , Finland
Athens, , Greece
Chandigarh, Punjab, India
Johannesburg, Gauteng, South Africa
Fremantle, Western Australia, Australia
Aschaffenburg, , Germany
Kochi, Kerala, India
Mumbai, Maharashtra, India
Padova, , Italy
Palermo, , Italy
Groningen, , Netherlands
Constanta, , Romania
Almería, , Spain
La Coruña, , Spain
Plymouth, , United Kingdom
Tustin, California, United States
Winnipeg, Manitoba, Canada
Schkeuditz, , Germany
Catanzaro, , Italy
Rio De Janeiro, , Brazil
Gentofte, , Denmark
Hyderabad, Andhra Pradesh, India
Karnal, Haryana, India
Eindhoven, , Netherlands
Maastricht, , Netherlands
Pretoria, Gauteng, South Africa
Salt Lake City, Utah, United States
Edmonton, Alberta, Canada
London, Ontario, Canada
Quebec, , Canada
Wangen, , Germany
Lodz, , Poland
Kingsport, Tennessee, United States
Roswell, Georgia, United States
Altoona, Pennsylvania, United States
Oulu, , Finland
Norwich, , United Kingdom
Tampere, , Finland
Satu Mare, , Romania
Bloemfontein, Free State, South Africa
Halifax, Nova Scotia, Canada
Smiths Falls, Ontario, Canada
Indore, Madhya Pradesh, India
Thriruvananthapuram, , India
Gaziantep, , Turkey
Cambridge, Ontario, Canada
Tumen, , Russian Federation
Ankara, , Turkey
Mission Hills, California, United States
Michigan City, Indiana, United States
Corpus Christi, Texas, United States
Schweinfurt, , Germany
Pulawy, , Poland
Chapel Hill, North Carolina, United States
Falkensee, , Germany
Dublin 9, , Ireland
Bydgoszcz, , Poland
Keswick, South Australia, Australia
Box Hill, Victoria, Australia
Beijing, Beijing, China
Krakow, , Poland
Blacktown, New South Wales, Australia
Kaoshiung, , Taiwan
Berlin, , Germany
Hyderbad, Andhra Pradesh, India
Madurai, Tamil Nadu, India
Kolkata, West Bengal, India
Goyang, , Korea, Republic Of
Nijmegen, , Netherlands
Odessa, Texas, United States
Caguas, , Puerto Rico
Chieti, , Italy
Antalya, , Turkey
Hull, , United Kingdom
South Burlington, Vermont, United States
Dublin, , Ireland
Craiova, Dolj, Romania
Montclair, California, United States
Nashville, Tennessee, United States
Belgrade, , Serbia
Bradenton, Florida, United States
Mississauga, Ontario, Canada
Gifhorn, , Germany
Mannheim, , Germany
Bayamon, , Puerto Rico
Pozuelo De Alarcon, , Spain
Nuneaton, , United Kingdom
Metairie, Louisiana, United States
Charleston, South Carolina, United States
Hamburg, , Germany
Arkhangelsk, , Russian Federation
Barnaul, , Russian Federation
Lawrenceville, Georgia, United States
Morehead City, North Carolina, United States
Iasi, , Romania
Sibiu, , Romania
Penza, , Russian Federation
Saratov, , Russian Federation
Smolensk, , Russian Federation
Huntsville, Alabama, United States
Aurora, Colorado, United States
Great Falls, Montana, United States
Lubbock, Texas, United States
Yaroslavl, , Russian Federation
Scarborough, Ontario, Canada
Sevilla, , Spain
Vantaa, , Finland
Durango, , Mexico
Monterrey, , Mexico
Nashua, New Hampshire, United States
Troy, Michigan, United States
Springfield, Missouri, United States
Smithtown, New York, United States
Tomball, Texas, United States
Valladolid, , Spain
Istanbul, , Turkey
Murrells Inlet, South Carolina, United States
Houston, Texas, United States
Bangalore, Karnataka, India
Chennai, Tamil Nadu, India
Seongnam Si, , Korea, Republic Of
Seoul, , Korea, Republic Of
Tainan City, , Taiwan
San Diego, California, United States
Crystal Lake, Illinois, United States
Mine Hill, New Jersey, United States
Cornwall, Ontario, Canada
Alberton, , South Africa
Interlochen, Michigan, United States
Petah Tikva, , Israel
Marília, , Brazil
Los Banos, California, United States
Whiteville, North Carolina, United States
Thessaloniki, , Greece
Bialystok, , Poland
Montreal, Quebec, Canada
Alabaster, Alabama, United States
Tempe, Arizona, United States
Little Rock, Arkansas, United States
Cerritos, California, United States
Fresno, California, United States
Los Angeles, California, United States
Watsonville, California, United States
Clearwater, Florida, United States
Deland, Florida, United States
Fort Lauderdale, Florida, United States
Kissimmee, Florida, United States
Saint Petersburg, Florida, United States
Tampa, Florida, United States
Indianapolis, Indiana, United States
West Des Moines, Iowa, United States
Lexington, Kentucky, United States
Monroe, Louisiana, United States
Natchitoches, Louisiana, United States
Bloomfield Hills, Michigan, United States
Dearborn, Michigan, United States
Saint Louis, Missouri, United States
Omaha, Nebraska, United States
Lebanon, New Hampshire, United States
Neptune, New Jersey, United States
Buffalo, New York, United States
Westfield, New York, United States
Burlington, North Carolina, United States
Greensboro, North Carolina, United States
Mooresville, North Carolina, United States
Cadiz, Ohio, United States
Cincinnati, Ohio, United States
Marion, Ohio, United States
Middleburg Heights, Ohio, United States
Beaver, Pennsylvania, United States
Hatfield, Pennsylvania, United States
Pittsburgh, Pennsylvania, United States
Uniontown, Pennsylvania, United States
Myrtle Beach, South Carolina, United States
Bartlett, Tennessee, United States
Longview, Texas, United States
San Antonio, Texas, United States
Schertz, Texas, United States
Spokane, Washington, United States
Madison, Wisconsin, United States
Douglas, Queensland, Australia
Herston, Queensland, Australia
Meadowbrook, Queensland, Australia
Oaklands Park, South Australia, Australia
Fitzroy, Victoria, Australia
Fortaleza, Ceara, Brazil
Aparecida De Goiania, Goias, Brazil
Curitiba, Parana, Brazil
Belém, Para, Brazil
Caxias Do Sul, Rio Grande Do Sul, Brazil
Porto Alegre, Rio Grande Do Sul, Brazil
Campinas, Sao Paulo, Brazil
Mogi Das Cruzes, Sao Paulo, Brazil
São Paulo, Sao Paulo, Brazil
Aracajú, , Brazil
Belo Horizonte, , Brazil
Goiânia, , Brazil
Joinville, , Brazil
Recife, , Brazil
Santos, , Brazil
Sao Paulo, , Brazil
Vancouver, British Columbia, Canada
St.John's, Newfoundland And Labrador, Canada
Thunder Bay, Ontario, Canada
Xiamen, Fujian, China
Zhenjiang, Jiangsu, China
Qingdao, Shandong, China
Plzen, , Czechia
Praha, , Czechia
Jarny, , France
Angermünde/Ot Wolletz, , Germany
Dillingen, , Germany
Elsterwerda, , Germany
Essen, , Germany
Karlsbad, , Germany
München, , Germany
Oldenburg, , Germany
Saint Ingbert Oberwürzbach, , Germany
Villingen Schwenningen, , Germany
Crete, , Greece
Guwahati, Assam, India
Manipal, Karnataka, India
Latina, , Italy
Tijuana, Baja California Norte, Mexico
Guadalajara, Jalisco, Mexico
Aguascalientes, , Mexico
San Luis Potosi, , Mexico
Goes, , Netherlands
Trondheim, , Norway
Tønsberg, , Norway
Katowice, , Poland
Poznan, , Poland
Ruda Slaska, , Poland
Warszawa, , Poland
Wroclaw, , Poland
Targu Mures, Mures, Romania
Timisoara, Timis, Romania
Bacau, , Romania
Deva, , Romania
Kazan, , Russian Federation
Lenasia, Gauteng, South Africa
Midrand, Gauteng, South Africa
Tongaat, Kwazulu Natal, South Africa
Somerset West, Western Cape, South Africa
Mora De Ebre, , Spain
Stockholm, , Sweden
Changhua City, , Taiwan
Izmir, , Turkey
Kayseri, , Turkey
Dubai, , United Arab Emirates
Devon, , United Kingdom
Glasgow, , United Kingdom
Livington, , United Kingdom
London, , United Kingdom
Manchester, , United Kingdom
St Helens, , United Kingdom
West Midlands, , United Kingdom
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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