Seborrheic Dermatitis: Ketoconazole 2% Foam Versus Ketoconazole 2% Shampoo

Launched by ST. LOUIS UNIVERSITY · Sep 14, 2010

Keywords

ClinConnect Summary

A wide variety of topical vehicles are available for medications that treat scalp disorders. Proper vehicle selection is important when managing scalp conditions, such as seborrheic dermatitis, because the efficacy of these treatments depends largely on compliance and the amount of active ingredient delivered to the scalp. It is therefore important to prescribe vehicles that are easy to apply and cause the least amount of disruption to the patients' pre-existing hair care practices. One of the most common rate limiting hair care practices among different cultures is wash frequency. Literatu...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • African American females aged 18 to 89 years
• • Previous diagnosis of seborrheic dermatitis of the scalp
• • TDSS between 50 and 200
• • Practice less than or equal to once weekly hair washing
• • Immunocompetent
• • Willing to not grease or oil scalp
• Exclusion Criteria:
• • Age below 18 years or above 89 years
• • Medical history of psoriasis, diabetes mellitus, immunosuppression, neurologic disorders, and/or chronic disease not stabilized by medication
• • Patients taking any oral steroids and/or antifungals within 30 days of enrollment
• • Sensitivity to any formulation components of either ketoconazole foam or shampoo including sulfur
• • The use of any topical medications including over the counter products indicated for the treatment of seborrheic dermatitis within 14 days of enrollment
• • Pregnant women, women who plan on becoming pregnant, or breastfeeding women
• • Current use or history of using any biologic medication