Regulation of Vitamin D Receptor (VDR),Calcium Sensing Receptor (CaSR), Cyclin D1,Ki67 and Proliferating Cell Nuclear Antigen (PCNA) in Primary Hyperparathyroidism
Launched by POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH, CHANDIGARH · Oct 26, 2010
Trial Information
Current as of May 14, 2025
Unknown status
Keywords
ClinConnect Summary
Introduction:
Primary hyperparathyroidism (PHPT) is the third most frequent endocrine disorder, after diabetes mellitus and thyroid disorders, that predominantly affects postmenopausal women, with an incidence of 1 -5 in 1000 people. It can occur at any age though young people are rarely affected. PHPT is characterized by hypersecretion of parathyroid hormone (PTH) and resultant hypercalcemia. Most cases of PHPT (\>85%) result from a solitary adenoma in one of the parathyroid glands. Multi-gland hyperplasia is found in about 10-15% of the patients while carcinoma occurs rarely (1-2%).
The...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patients with surgically verified sporadic PHPT
- Exclusion Criteria:
- • Patients with hyperplasia, renal failure and multiple endocrine neoplasia
About Post Graduate Institute Of Medical Education And Research, Chandigarh
The Post Graduate Institute of Medical Education and Research (PGIMER) in Chandigarh is a premier institute dedicated to advancing medical education, research, and healthcare delivery in India. Renowned for its commitment to excellence, PGIMER plays a pivotal role in conducting cutting-edge clinical trials that contribute to the development of innovative therapies and improve patient outcomes. With a multidisciplinary approach and a team of highly qualified professionals, PGIMER fosters a collaborative environment for research, aiming to enhance medical knowledge and practice through rigorous scientific inquiry and evidence-based solutions.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Chandigarh, Ut, India
Patients applied
Trial Officials
Dr Sanjay K. Bhadada, DM
Principal Investigator
Indian Counsil of Medical Research
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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