In Vitro Maturation (IVM) for Polycystic Ovary Syndrome (PCOS)

Launched by UNIVERSITY REPRODUCTIVE ASSOCIATES · Nov 8, 2010

Keywords

ClinConnect Summary

No description provided

Gender

FEMALE

Eligibility criteria

• • Inclusion Criteria
• • 1. 10 women between the ages of 18-34 inclusive at time of signing Informed Consent Form.
• • 2. A diagnosis of PCOS by their primary MD
• • 3. An Antral Follicular Count (AFC) of \> 12 on one ovary on at least one occasion
• • 4. A day 3 FSH level of \<8 IU/mL
• • 5. In good general health off of current medications which may confound response to study medications.
• • 6. Desire to seek pregnancy actively during the study period by IVF-ICSI.
• • 7. A normal uterine cavity must have been confirmed by either hydrosonogram or hysteroscopy within two years of entering the study.
• • 8. Male partner able to provide adequate semen sample by ejaculation (no TESE)
• • Exclusion Criteria
• • 1. Current pregnancy
• • 2. Patients with uncorrected thyroid disease (defined as TSH \< 0.2 mIU/ML or \>5.5 mIU/mL). A normal level within the last year is adequate for entry.
• • 3. Patients with poorly controlled diabetes (HgB A1C over 8.0 ng/dL).
• • 4. Patients enrolled simultaneously into other investigative studies that require medications, proscribe the study medications, limit intercourse, or otherwise prevent compliance with the protocol.
• • 5. Patients with significant anemia (Hemoglobin \< 10 mg/dL).
• • 6. Patients enrolled simultaneously into other investigative studies that would interfere with this research study.
• • 7. have any contraindications to using birth control pills (oral contraceptives) as determined by the attending physician (e.g. history of thromboembolism or estrogen-dependent malignancy, such as breast cancer, etc.) -