Predictive Questionnaires for Risk of Acute COPD (Chronic Obstructive Pulmonary Disease) Exacerbations

Launched by ASTRAZENECA · Nov 24, 2010

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Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent
• • Age ≥ 40 years
• • Patients fulfilling criteria for COPD according to the Global initiative for chronic obstructive pulmonary disease (GOLD) stage I or higher
• • Smokers or ex-smokers of at least 10 pack-years
• * Patients suffering an AECOPD either:
• • 1. Admitted to hospital due to AECOPD (severe exacerbation) or
• • 2. Confirmed AECOPD at GP (general practitioner) setting (moderate exacerbation) Definition AECOPD: Increase in respiratory symptoms requiring treatment with oral corticosteroids, antibiotics or both.
• Exclusion Criteria:
• • Patients who have never smoked
• • Patients with active long-term respiratory disease (e.g. bronchial asthma, cystic fibrosis, severe bronchiectasis, malignancy, restrictive lung diseases etc.)
• • Exacerbation of COPD due to other causes such as pneumothorax and acute decompensated congestive heart failure
• • Difficulties in communication (cognitive deterioration, sensorial disability, language barriers)
• • Severe disease with poor vital prognosis (life length expectancy less than one year)