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Search / Trial NCT01350037

Alfentanil Versus Remifentanil in Patient-controlled Sedation During Endoscopic Retrograde Cholangiopancreatography (ERCP)

Launched by HELSINKI UNIVERSITY CENTRAL HOSPITAL · May 6, 2011

Trial Information

Current as of April 28, 2025

Completed

Keywords

Patient Controlled Sedation Propofol Alfentanil Remifentanil Endoscopic Retrograde Cholangiopancreatography

ClinConnect Summary

Deep sedation with propofol has been suggested necessary for successful performance of endoscopic retrograde cholangiopancreatography (ERCP).Airway obstruction, hypoventilation and hypoxemia occurs in deeply sedated patients with a high incidence of 12-30%.As a result of frequent hypoxemia events, deep sedation is associated with increased morbidity and mortality.Careful monitoring of vital signs and involving of anesthesia-trained personal are recommended for deeply sedated patients.Self-administration of propofol by the patient him- or herself (patient-controlled sedation, PCS)could be a ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • elective ERCP patients
  • Exclusion Criteria:
  • allergy to propofol or opioid analgesics, drug addiction, inability to co-operate, ASA class greater than 3, or patient's refusal.

About Helsinki University Central Hospital

Helsinki University Central Hospital (HUCH) is a leading academic medical institution in Finland, dedicated to advancing healthcare through innovative research and clinical excellence. As a pivotal sponsor of clinical trials, HUCH integrates cutting-edge medical practices with rigorous scientific inquiry, fostering collaborations between researchers, healthcare professionals, and patients. The hospital is committed to enhancing patient outcomes and contributing to the global body of medical knowledge by conducting high-quality, ethically sound clinical studies across a diverse range of therapeutic areas. With a strong emphasis on education and training, HUCH plays a vital role in shaping the next generation of healthcare leaders and researchers.

Locations

Helsinki, Uusimaa, Finland

Patients applied

0 patients applied

Trial Officials

Reino Pöyhiä, MD,PhD

Study Director

Helsinki University Central Hospital, Department of Anesthesiology and Intensive Care

Maxim Mazanikov, MD

Principal Investigator

Helsinki University Central Hospital,Department of Anesthesiology and Intensive Care

Martti Färkkilä, MD,Professor

Principal Investigator

Helsinki University Central Hospital,Department of Medicine, Division of Gastroenterology

Leena Kylänpää, MD,PhD

Principal Investigator

Helsinki University Central Hospital,Department of Gastrointestinal and General Surgery

Jorma Halttunen, MD,PhD

Principal Investigator

Helsinki University Central Hospital,Department of Gastrointestinal and General Surgery

Outi Lindström, MD,PhD

Principal Investigator

Helsinki University Central Hospital,Department of Gastrointestinal and General Surgery

Harri Mustonen, DSc

Principal Investigator

Helsinki University Central Hospital, Department of Surgery

Marianne Udd, MD,PhD

Principal Investigator

Helsinki University Central Hospital,Department of Gastrointestinal and General Surgery

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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