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Search / Trial NCT01414361

Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Aug 10, 2011

Trial Information

Current as of June 20, 2025

Unknown status

Keywords

Coronary Artery Stenosis Fractional Flow Reserve Intravascular Ultrasonography

ClinConnect Summary

Both physiologic information from fractional flow reserve (FFR) and anatomical information from intravascular ultrasound (IVUS) in assessing intermediate coronary stenotic lesions are useful. Functional significance of a coronary stenosis is determined by both the severity of a stenosis and the amount of myocardium supplied. Therefore, when the functional significance of a lesion is assessed by lumen area measured by IVUS, different criteria should be applied according to lesion location and anatomical variations of the coronary artery. However, previous studies included only patients with ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Intermediate coronary stenosis by visual estimation
  • Exclusion Criteria:
  • history of coronary artery bypass graft surgery
  • previously revascularized lesion
  • creatinine \> 1.6 mg/dL or eGFR \< 30 ml/min/1.73m2 pre-procedure per institutional standards
  • known pregnancy
  • contrast agent allergy that cannot be adequately premedicated
  • severe PVD precluding cardiac catheterization
  • patient not a candidate for IVUS and FFR
  • inability or unwillingness to provide informed consent
  • inability or unwillingness to perform required follow up procedures

About Seoul National University Hospital

Seoul National University Hospital (SNUH) is a leading medical institution in South Korea, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, SNUH integrates cutting-edge scientific inquiry with patient-centered care, facilitating the development of novel therapies and treatment protocols. The hospital boasts a diverse range of specialized departments and a robust infrastructure for conducting clinical studies, ensuring rigorous adherence to ethical standards and regulatory compliance. By fostering collaboration among multidisciplinary teams, SNUH aims to contribute significantly to global medical advancements and improve patient outcomes.

Locations

Seoul, , Korea, Republic Of

Patients applied

0 patients applied

Trial Officials

Bon-Kwon Koo, MD, PhD

Principal Investigator

Seoul National University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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