Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD

Launched by MAASTRICHT UNIVERSITY MEDICAL CENTER · Aug 16, 2011

Keywords

ClinConnect Summary

In this study we investigate whether milk based protein sources of BCAA (casein and whey proteins) are superior to soy protein in the stimulation of protein anabolism before, during and after cycle exercise in COPD and healthy elderly and young subjects, and whether adding BCAA to soy protein will increase protein anabolism in these subjects.

To investigate Leucine, Isoleucine and Valine metabolism during and after exercise in COPD and healthy subjects

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Irreversible chronic airflow limitation (FEV1 \<70% of predicted)
• • Clinically stable condition
• Exclusion Criteria:
• • Oxygen supplementation
• • Respiratory tract infection or exacerbation of his disease at least 4 weeks prior to the study
• • Oral corticosteroids as maintenance medication
• • Other concomitant metabolic disease (ie malignancy, cardiac failure, recent surgery, severe endocrine, hepatic or renal disorder)

Trial Officials