Efficacy of Buffered Hypertonic Saline(BHS)Nasal Irrigation in Allergic Rhinitis (AR) Children
Launched by THAMMASAT UNIVERSITY · Sep 27, 2011
Trial Information
Current as of May 18, 2025
Completed
Keywords
ClinConnect Summary
1. BHS is superior to NSS for improving mucociliary function that by measure saccharine clearance time(SCT)at 10 minute after nasal irrigation compare to baseline.
2. BHS is superior to NSS for clinical effectiveness at short period and 1 month follow up
* at short period: compare the following results at baseline and 10 minute after nasal irrigation
1. total nasal symptom score(TNSS)
2. satisfaction to nasal irrigation
3. side effect
* at 2 and 4 weeks follow up : compare the following results at baseline and 10 minute after nasal irrigation
1. quality of life(...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. age 6-15 years
- • 2. diagnosed AR obtained by history, physical examination and positive skin prick test or nasal cytology
- • 3. TNSS ≥ 4 at the first visit of this study
- Exclusion Criteria:
- • 1. Patients with a history of nasal anatomical defects
- • 2. Abnormal nasal ciliary function or an upper respiratory tract infection in the preceding 2 weeks
About Thammasat University
Thammasat University, a leading academic institution in Thailand, is dedicated to advancing medical research and education through its various faculties and research centers. With a commitment to fostering innovative healthcare solutions, the university sponsors clinical trials aimed at enhancing patient outcomes and addressing pressing health challenges. Leveraging a multidisciplinary approach, Thammasat University collaborates with healthcare professionals and researchers to ensure rigorous scientific methodologies and ethical standards are upheld in all its clinical research endeavors. Through these initiatives, the university seeks to contribute significantly to the global body of medical knowledge and improve public health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Klong Luang, Pratumthanee, Thailand
Patients applied
Trial Officials
Araya Satdhabudh, MD
Principal Investigator
Thammasat University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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