Acetic Acid Guided Biopsies Compared With High Definition Endoscopy in the Detection of Barrett's Esophagus
Launched by JOHANNES GUTENBERG UNIVERSITY MAINZ · Sep 27, 2011
Trial Information
Current as of May 08, 2025
Unknown status
Keywords
ClinConnect Summary
Specialized columnar epithelium (SCE) is considered as pathognomonic for Barrett's esophagus and can be recognized by new endoscopic techniques. Aim of the study is to test the efficacy of HD+ endoscopy in conjunction with i-scan (newly developed post processing digital filter) or chromoendoscopy (acetic acid) to diagnose Barrett's esophagus.
Patients with visible columnar lined lower esophagus (CLE) or known Barrett's esophagus are included. After standardized PPI therapy (14 days; standard dosage) patients are randomized at a 1:1 ratio to undergo either chromoendoscopy in conjunction wit...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients with CLE
- • patients with known Barrett's esophagus
- Exclusion Criteria:
- • pregnancy
- • severe coagulopathy
- • known malignancies
About Johannes Gutenberg University Mainz
Johannes Gutenberg University Mainz, a leading research institution in Germany, is dedicated to advancing medical science through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates cutting-edge research and education to address critical health challenges. Its commitment to ethical standards and scientific rigor ensures that clinical trials are conducted with the utmost integrity, aiming to translate research findings into effective therapies and improved patient outcomes. Through its robust infrastructure and expert faculty, Johannes Gutenberg University Mainz plays a pivotal role in enhancing the landscape of clinical research and contributing to global health advancements.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Mainz, , Germany
Patients applied
Trial Officials
Arthur Hoffman, MD
Principal Investigator
Johannes Gutenberg University Mainz
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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