Eyelid Warming Technology for Meibomian Gland Dysfunction

Launched by SINGAPORE NATIONAL EYE CENTRE · Oct 6, 2011

Keywords

ClinConnect Summary

Study Objectives and Purpose:

1. A primary purpose of the study is to compare the efficacy of novel eyelid warming devices (Blephasteam and EyeGiene) for treatment of meibomian gland dysfunction by objective clinical scoring and objective assessment of ocular surface parameters in an Asian population.
2. The second aim is to assess the patient acceptance of these modalities, in terms of comfort and convenience.
3. A third aim of the study is to document Meibomian gland disease using non-invasive Meibography, and the possible alterations of this condition after treatment.

Study Design: Pro...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Eyelids must present with blocked meibomian gland openings (plugs), at least 1 visible MG plug in the 4 eyelids, or discernable change in consistency of meibum when MG expressed in upper or lower eyelids.
• • At least one out of 8 questions on dry eye symptoms is answered with often or all the time (Appendix C, Questionnaire modified after Schein et al.,1997).
• • Eyes should not show any other ocular surface pathology which required more treatment than eye lubricant and conventional eyelid hygiene.
• Exclusion Criteria:
• • Known history of thyroid disorders (diagnosed by physician).
• • No ocular surgery within the previous 6 months and LASIK within the previous 1 year.
• • Any intake of central nervous system and hormonal drugs within last 30 days and inability to withhold such drugs for at least 6 weeks.
• • Active ocular infection or pterygium.
• • Anticipated necessity to wear contact lens in the duration of the study.
• • Living in the same household as another participant of the study.
• • Any other specified reason as determined by clinical investigator, for example, the need to use any treatment or eyedrops (eg. Restasis) not permitted by the study.