Endometrial Receptivity After GnRH Agonist Triggering

Launched by IVI MADRID · Dec 28, 2011

Keywords

ClinConnect Summary

No description provided

Gender

FEMALE

Eligibility criteria

• Inclusion criteria :
• • Healthy oocyte donor women
• • Aged 18-35 years
• • With a menstrual cycle length of 26-35 days
• • Normal ultrasound scan of uterus and ovaries
• • Normal basal hormones
• • No contraindication for controlled ovarian stimulation (COS)
• • Willing to participate in the study and providing written informed consent.
• Exclusion Criteria:
• • Subjects with current or previous history of an endocrine abnormality
• • Subjects with an abnormal outcome of blood biochemistry or hematology
• • Subjects with an abnormal cervical smear
• • Subjects with a chronic disease
• • Subjects with any relevant ovarian-, tubal- or uterine-pathology that could interfere with the COS treatment
• • Pregnancy
• • Subjects who had a previous history of ovarian hyperresponse or ovarian hyperstimulation syndrome (OHSS), polycystic ovary syndrome (PCOS) or a basal antral follicle count (AFC) of more than 20 on ultrasound (11 mm, both ovaries combined) .
• • Previous low ovarian response to FSH or hMG treatment (i.e. cycle cancelled due to insufficient ovarian response or less than 6 oocytes obtained).
• • A history of recurrent miscarriage,
• • Smoking more than 10 cigarettes per day.
• • Not willing to comply with study procedures

Trial Officials