Guideline-based Pacing Therapy for Reflex Syncope

Launched by GRUPPO ITALIANO MULTIDISCIPLINARE PER LO STUDIO DELLA SINCOPE · Jan 12, 2012

Keywords

ClinConnect Summary

Background Divergence of opinion exists regarding the efficacy of cardiac pacing in patients affected by different forms of reflex syncope.

Definitions.

Severe syncope is defined when:

* it is perceived by patient that it alters his/her quality of life, and
* is unpredictable because occurs without, or with very short prodromes \< 10 sec (thus exposing patients to risk of trauma) or, if preceded by prodromes, syncope recurs despite appropriate therapies (CPM or drugs).

Recurrent syncopes: at least 2 episodes during the last year (including the index episode) or 3 episodes during the las...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients affected by severe, recurrent, certain or suspected (undetermined) reflex syncopes, aged ≥ 40 years.
• Exclusion Criteria:
• • Reflex syncopes due to reversible causes, e.g., vasoactive drugs, concomitant diseases, etc
• • Suspected of certain cardiac syncope
• • Syncope caused by orthostatic hypotension
• • Non-syncopal causes of transient loss of consciousness