Saline Irrigation After Surgery in Patients With Chronic Sinusitis
Launched by SAMUEL LUNENFELD RESEARCH INSTITUTE, MOUNT SINAI HOSPITAL · Apr 9, 2012
Trial Information
Current as of May 18, 2025
Completed
Keywords
ClinConnect Summary
Background: Chronic Rhinosinusitis (CRS) is a common inflammatory condition of the upper respiratory tract lasting more than 8 to 12 weeks. Major symptoms include facial congestion/fullness, facial pain/pressure, nasal obstruction/blockage, purulent nasal drainage, and reduction or loss of smell. The diagnosis must include two major symptoms and either endoscopic evidence of polyps, edema or mucopurulent discharge from the middle meatus and/or CT changes in the mucosa of sinuses or osteomeatal complexes.1
CRS has an estimated prevalence of 5% in the Canadian population2, and up to 16% in s...
Gender
ALL
Eligibility criteria
- Inclusion criteria:
- • Documented diagnosis of unilateral or bilateral CRS
- • Documented failed medical treatment of CRS
- • Eighteen (18) to sixty-five (65) years of age
- • Planned ESS for the treatment of CRS
- • Able to read and understand English
- Exclusion criteria:
- • Pregnant
- • Cystic Fibrosis
- • Diagnosed immotile cilia syndrome
- • Diagnosed immunodeficiency syndrome
- • Diagnosed fungal sinusitis
- • Sinonasal tumours or obstructive lesions
About Samuel Lunenfeld Research Institute, Mount Sinai Hospital
The Samuel Lunenfeld Research Institute at Mount Sinai Hospital is a leading biomedical research facility dedicated to advancing our understanding of human health and disease. Renowned for its innovative research programs, the institute focuses on areas such as cancer, genetics, and reproductive health, fostering collaboration among top-tier scientists and clinicians. With a commitment to translating research findings into clinical applications, the Samuel Lunenfeld Research Institute plays a pivotal role in the development of novel therapies and interventions, thereby contributing to improved patient outcomes and the advancement of medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Calgary, Alberta, Canada
London, Ontario, Canada
Ottawa, Ontario, Canada
Toronto, Ontario, Canada
Patients applied
Trial Officials
Ian J Witterick, MD MSc FRCSC
Principal Investigator
Samuel R Lunenfeld Institute
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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