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Search / Trial NCT01615328

Evaluation of Fusion Rate of Anterior Cervical Discectomy and Fusion (ACDF) Using Cervios ChronOs™ and Bonion™

Launched by SEOUL NATIONAL UNIVERSITY HOSPITAL · Jun 7, 2012

Trial Information

Current as of May 22, 2025

Completed

Keywords

Anterior Cervical Discectomy And Fusion Bone Graft Substitute Peek Cage Hydroxyapatite Demineralized Bone Matrix B Tricalcium Phosphate Bonion Cervios Chron Os

ClinConnect Summary

Biologically, graft material should be endowed with several basic properties. Several synthetic materials and graft substitutes have been developed to maximize fusion outcomes while avoiding complications of harvesting autograft. Mixture of hydroxyapatite (HA) and β-tricalcium phosphate (β-TCP), have been widely utilized for bony regeneration. On the other hand, demineralized bone matrix (DBM) has been utilized as a graft substitute with mainly its osteoinductive ability. While HA and β-TCP have osteoinductive osteoconductive properties and DBM has osteoconductive osteoinductive properties,...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Clinical diagnosis of cervical HIVD, CSR, CSM or OPLL
  • The patient who is expected to receive anterior cervical discectomy and fusion operation.
  • Volunteer for this study with written consent.
  • Exclusion Criteria:
  • Patient with cervical spine fracture, infection.
  • Below -3.5 T-score by DEXA bone densitometry
  • Patient with hemorrhagic diseases
  • Patient with malignancy
  • Patient who is not suitable for this study judged by principal investigator

About Seoul National University Hospital

Seoul National University Hospital (SNUH) is a leading medical institution in South Korea, renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, SNUH integrates cutting-edge scientific inquiry with patient-centered care, facilitating the development of novel therapies and treatment protocols. The hospital boasts a diverse range of specialized departments and a robust infrastructure for conducting clinical studies, ensuring rigorous adherence to ethical standards and regulatory compliance. By fostering collaboration among multidisciplinary teams, SNUH aims to contribute significantly to global medical advancements and improve patient outcomes.

Locations

Seongnam Si, Gyeonggi Do, Korea, Republic Of

Patients applied

0 patients applied

Trial Officials

Jin Sup Yeom, MD, PhD

Principal Investigator

Seoul National Univerity Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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