Monitoring Anticoagulant Therapy in Antiphospholipid Syndrome
Launched by JOHANN WOLFGANG GOETHE UNIVERSITY HOSPITAL · Aug 6, 2012
Trial Information
Current as of May 02, 2025
Completed
Keywords
ClinConnect Summary
Patients with an antiphospholipid syndrome receiving Vitamin-K antagonists for secondary prevention after a first thrombotic complication are known to be at higher risk of recurrent thrombotic events despite INR values in the therapeutic range. It ist also known that antiphospholipid antibodies can interfere with phospholipid-dependent tests (e.g. prothrombin time and INR).
The primary objective of this study is to determine the prevalence of interfering antiphospholipid antibodies. The intensity of anticoagulant therapy was assessed by measuring the INR using different thromboplastins and...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • age 18-90 years
- Exclusion Criteria:
- • none
About Johann Wolfgang Goethe University Hospital
Johann Wolfgang Goethe University Hospital, located in Frankfurt am Main, Germany, is a prominent academic medical center affiliated with Goethe University. Renowned for its commitment to advancing healthcare through innovative research and clinical excellence, the hospital serves as a vital hub for clinical trials and medical studies. It integrates cutting-edge technology with a multidisciplinary approach, facilitating collaboration among healthcare professionals to enhance patient outcomes. The hospital is dedicated to ethical research practices and adheres to stringent regulatory standards, ensuring the safety and well-being of trial participants while contributing to the advancement of medical science.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Frankfurt/Main, Hessen, Germany
Patients applied
Trial Officials
Birgit Linnemann, MD
Principal Investigator
Goethe University Hospital, Division of Vascular Medicine
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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