Randomized Controlled Trial of ImmuKnow in Liver Transplantation
Launched by UNIVERSITY OF BOLOGNA · Jan 7, 2013
Trial Information
Current as of June 05, 2025
Completed
Keywords
ClinConnect Summary
We performed a randomized prospective interventional trial where the Interventional group had immunosuppression modified according to ImmuKnow values. Immunosuppression was decreased by 25% if ImmuKnow values were less than 130 ng/mL ATP. Similarly, immunosuppression was increased by 25% if ImmuKnow values were greater than 450 ng/mL ATP. Immunosuppression of the Control group was managed by the Standard of Care at our institution. ImmuKnow was performed before liver transplant, after surgery and at each clinic visit with the approximate schedule: day 1; weekly, weeks 1-4; week 6; week 8; m...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • consecutive adult liver transplant recipients at our center;
- • patients not entered into other studies;
- • provided consent.
- Exclusion Criteria:
- • available follow-up;
- • consent removed.
About University Of Bologna
The University of Bologna, one of the oldest and most prestigious academic institutions in the world, is dedicated to advancing knowledge and innovation in the field of healthcare through rigorous clinical research. With a strong emphasis on interdisciplinary collaboration and cutting-edge methodologies, the university sponsors a diverse range of clinical trials aimed at enhancing patient outcomes and contributing to the scientific community. Its commitment to ethical standards and regulatory compliance ensures that all trials are conducted with the utmost integrity, fostering an environment of trust and excellence in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Antonio Daniele Pinna, MD
Study Director
Department of General Surgery and Transplantation; S.Orsola-Malpighi Hospital, University of Bologna
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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