Effect of Folic Acid Supplementation on Plasma Homocysteine Level in Obese Children
Launched by QUEEN SIRIKIT NATIONAL INSTITUTE OF CHILD HEALTH · Jan 9, 2013
Trial Information
Current as of April 27, 2025
Completed
Keywords
ClinConnect Summary
Atherosclerosis is common \& remains a significant clinical problem because of leading to myocardial infarction, stroke and cardiovascular death. Many studies founded hyperhomocysteinemia is an independent risk factor for those cardiovascular diseases which take responsible for about 10% of total cardiovascular disease risk. Reduction of elevated plasma homocysteine may prevent up to 25% of cardiovascular events. One of modifiable cause of hyperhomocysteinemia is prevention of vitamin deficiency, especially folate deficiency.
Obese Thai children are probable risk for folate deficiency due ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient age between 9-18 years
- • Diagnosed obesity (BMI more than median plus two of standard deviation for age and sex according to WHO reference 2007)
- Exclusion Criteria:
- • Secondary obesity
- • Thalassemia disease
- • Renal and hepatic dysfunction
- • Drugs: anticonvulsant, estrogen, thiazides, metformin, cholestyramine, methotrexate, fibrates, nicotinic acid
- • Previous vitamin supplementation 1 month before study
About Queen Sirikit National Institute Of Child Health
The Queen Sirikit National Institute of Child Health (QSNICH) is a leading clinical research organization dedicated to advancing pediatric healthcare through innovative research and clinical trials. Situated in Thailand, the institute focuses on improving health outcomes for children by conducting rigorous scientific studies that address critical health issues affecting the pediatric population. With a commitment to excellence, QSNICH collaborates with various stakeholders, including healthcare providers, academic institutions, and international organizations, to enhance the understanding of childhood diseases and develop effective interventions. Their mission is to foster a comprehensive approach to child health, ensuring that every child has access to the best possible care and treatment options.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bangkok, , Thailand
Bangkok, , Thailand
Patients applied
Trial Officials
Orawan Iamopas, MD.
Principal Investigator
Queen Sirikit National Institute of Child Health
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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