Impact of CVVHD With Adsorption Capacity Membranes in Septic Acute Kidney Injury

Launched by HOSPITAL UNIVERSITARI DE BELLVITGE · Feb 12, 2013

Keywords

ClinConnect Summary

Investigators will warrant a correct protocol application. Study data will be reviewed by an external monitoring committee from the clinical assay research central unit (UCICEC - IDIBELL). Monitors will contrast registered data from the collection data form (CDF) with data from patient´s medical record. All patient´s medical records will be indefinitely saved in electronical format to be reviewed if necessary.

Patients who meet inclusion criteria will be randomized for one of both arms with aleatory assignation using a randomisation sequential (RndSeq) program for Statistical Package for t...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Less than 72 hours from ICU admission to inclusion
• • Clinical diagnosis of Severe Sepsis or Septic shock (SCCM definitions)
• • Correct therapeutic initial management of septic process (SSC guidelines)
• • Clinical diagnosis of Acute Kidney Injury (ADQI definitions)
• • Acute Kidney Injury meeting CRRT initiation criteria (ADQI guidelines)
• • Written informed consent from patient or legal surrogates
• Exclusion Criteria:
• • End Stage Renal Disease(ESRD)
• • Received previous CRRT or hemodialysis in the last three months
• • Inclusion in other ongoing study
• • Coexisting illness with a high probability of death
• • Immunosuppression

Trial Officials