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Search / Trial NCT01790698

Systems Medicine to Study Necrotizing Soft Tissue Infections (NSTIs).

Launched by KAROLINSKA INSTITUTET · Feb 11, 2013

Trial Information

Current as of May 07, 2025

Completed

Keywords

Necrotizing Fasciitis Streptococcus Pyogenes Staphylococcus Aureus Immunopathogenesis

ClinConnect Summary

Patients will be prospectively recruited at 5 clinical centers (Rigshospitalet, Karolinska University Hospital, Blekinge University, Sahlgrenska University and University of Bergen). Clinical definition criteria for NSTI: NSTI is a clinical diagnosis. Initial signs are the occurrence of erythema, pain or tenderness beyond margins of erythema and swelling. Imaging and laboratory tests have little predictive value in the early stage. The gold standard modality for diagnosis of NSTI remains operative exploration. Operative findings that are consistent with NSTI include "dishwater or foul smell...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Necrotizing soft tissue infections
  • Exclusion Criteria:
  • Patients under the age of 18 years

About Karolinska Institutet

Karolinska Institutet is a renowned medical university located in Sweden, recognized for its commitment to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the institution focuses on translating scientific discoveries into effective treatments and therapies, emphasizing patient-centered approaches. With a strong emphasis on collaboration and interdisciplinary research, Karolinska Institutet plays a pivotal role in addressing global health challenges and improving patient outcomes, leveraging its extensive network of experts and state-of-the-art facilities to drive clinical advancements.

Locations

Copenhagen, , Denmark

Gothenburg, , Sweden

Stockholm, , Sweden

Bergen, , Norway

Gothenburg, , Sweden

Karlskrona, , Sweden

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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