Modified ORS Solution for Severely Malnourished Children
Launched by INTERNATIONAL CENTRE FOR DIARRHOEAL DISEASE RESEARCH, BANGLADESH · Mar 29, 2013
Trial Information
Current as of June 20, 2025
Completed
Keywords
ClinConnect Summary
Study Design This will be a randomized, double-blind, controlled clinical trial to assess the efficacy of three different modified ORSs: (i) Currently recommended ORS with some modification (Na+ 75, K 40 mmol/L and added minerals); (ii) Resomal (Na+ 45); (iii) Currently recommended ORS (Na+ 75 , K 40 mmol/L and added minerals) with added benefiber (25 grams/L) in the treatment of acute watery diarrhoea in children with severe malnutrition.
STUDY POPULATION Children of either sex, aged 6 months to 3 years, presenting with acute watery diarrhoea of \<7 days duration will be screened.
Sample...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Some or severe dehydration (assessed by WHO Guidelines).
- • Weight for height (W/H) \<70% of NCHS median or with bipedal edema.
- • Written informed consent from parents/ guardians
- Exclusion Criteria:
- • Blood or mucus in stools
- • Have received antidiarhoeal drugs for their diarrhoea
- • Severe diseases (e.g. severe pneumonia with respiratory distress, clinical sepsis, meningitis) requiring intensive care and other ancillary support like O2 inhalation, oropharyngeal suction etc.
About International Centre For Diarrhoeal Disease Research, Bangladesh
The International Centre for Diarrhoeal Disease Research, Bangladesh (ICDDRB) is a renowned research organization dedicated to addressing pressing public health challenges, particularly in the fields of infectious diseases and nutrition. Established in 1960, ICDDRB combines rigorous scientific research with robust clinical trials to develop innovative solutions for diarrheal diseases and other related health issues affecting vulnerable populations. With a commitment to improving health outcomes through evidence-based interventions, ICDDRB collaborates with global health partners and utilizes its extensive expertise in epidemiology, microbiology, and clinical medicine to advance knowledge and enhance healthcare delivery in Bangladesh and beyond.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dhaka, , Bangladesh
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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