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Search / Trial NCT01828905

Cerament Treatment of Fracture Defects

Launched by JOHANNES GUTENBERG UNIVERSITY MAINZ · Apr 8, 2013

Trial Information

Current as of May 28, 2025

Completed

Keywords

Tibia Fracture Bone Graft Iliac Crest Bone Graft Substitute Cerament Void Filler Quality Of Life Pain Costs Of Care

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • patients with traumatic, closed, depression fracture of the proximal tibia (limited to AO type B2 \& B3)
  • solitary trauma
  • candidate for bone grafting
  • patients between the age of 18 and 65 years
  • written informed consent obtained before any study-related activities
  • patients with communicative ability to understand the procedure and participate in the study and comply with the follow up program
  • Exclusion Criteria:
  • patients with multiple injuries
  • polytrauma patients
  • compartment syndrome
  • previous iliac crest bone graft harvesting
  • local infection at the site of implantation
  • chronic pain disease
  • malignancy
  • rheumatoid arthritis
  • chronic cortisone intake
  • X-ray diagnostics not available, fracture cannot be classified
  • clinically significant or unstable medical or surgical condition that may preclude safe and complete study participation
  • a pre-existing calcium metabolism disorder (e.g. hypercalcemia)
  • known hyperthyroidism or autonomous thyroid adenoma
  • history of serious reaction to iodine based radio contrast agents
  • women who are pregnant or breastfeeding
  • irreversible coagulopathy or bleeding disorder
  • history of physical or psychological condition that contraindicates the use of an investigational device or render the patient at high risk from treatment complications
  • history of hypersensitivity to the investigational device or any of its ingredients
  • participation in other clinical trials during the present clinical trial or within the last 1 month

About Johannes Gutenberg University Mainz

Johannes Gutenberg University Mainz, a leading research institution in Germany, is dedicated to advancing medical science through innovative clinical trials. With a strong emphasis on interdisciplinary collaboration, the university integrates cutting-edge research and education to address critical health challenges. Its commitment to ethical standards and scientific rigor ensures that clinical trials are conducted with the utmost integrity, aiming to translate research findings into effective therapies and improved patient outcomes. Through its robust infrastructure and expert faculty, Johannes Gutenberg University Mainz plays a pivotal role in enhancing the landscape of clinical research and contributing to global health advancements.

Locations

München, Bavaria, Germany

Freiburg, Geogr. Baden Wuerttemberg, Germany

Bad Homburg, Hesse, Germany

Frankfurt, Hesse, Germany

Fulda, Hesse, Germany

Rüsselsheim, Hesse, Germany

Aachen, Northrhine Westfalia, Germany

Cologne, Northrhine Westfalia, Germany

Duisburg, Northrhine Westfalia, Germany

Düsseldorf, Northrhine Westfalia, Germany

Münster, Northrhine Westfalia, Germany

Koblenz, Rhineland Palatinate, Germany

Ludwigshafen, Rhineland Palatinate, Germany

Worms, Rhineland Palatinate, Germany

Mainz, Rhineland Palatine, Germany

Lübeck, Schleswig Holstein, Germany

Patients applied

0 patients applied

Trial Officials

Pol M. Rommens, Univ.-Prof., MD

Principal Investigator

Department of Orthopaedics and Traumatology, Johannes Gutenberg University Mainz

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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