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Search / Trial NCT01833676

To Compare Effect of Sevoflurane Versus Desflurane on the Return of Swallowing Reflexes in the Elderly

Launched by UNIVERSITY OF MALAYA · Apr 14, 2013

Trial Information

Current as of May 12, 2025

Completed

Keywords

Sevoflurane Desflurane Protective Airway Reflexes Elderly

ClinConnect Summary

This is a prospective, double-blind, randomized controlled trial by single operator. American Society of Anaesthesiologists' classification of physical status I-II male and female patients aged 60-85 year scheduled to have general anesthesia for surgical procedures were recruited. Patients recruited will be given 20mls of water to swallow in the upright position prior to surgery after obtaining informed consent. All patients enrolled are judged to have adequate swallowing if no coughing or drooling occurred after the water passed into the mouth, and no water remained in the oropharynx upon ...

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age 60-85 years' old
  • Both male and female patients
  • ASA I-II
  • Body mass index (BMI) ≤ 30 kg/m2
  • Elective surgery under general anaesthesia with the use of laryngeal mask airway (LMA) / LMA Proseal / LMA Supreme
  • Type of surgery: Urogynecological, General Surgery, Orthopedics, Eye, Vascular, Plastic
  • Surgery/anaesthesia lasting for 0.5-3 hours
  • Exclusion Criteria:
  • Patients with difficulty in swallowing, preexisting neuromuscular or central nervous system disorder
  • Patients undergoing intra abdominal, thoracic, face, nasal or throat surgery
  • Known condition interfering with gastric emptying
  • Patients with cognitive or hearing impairment and inability to provide informed consent
  • ASA III-IV patients
  • Use of muscle relaxant during the course of general anesthesia
  • Contraindication or previous adverse response to any of the study drugs

About University Of Malaya

The University of Malaya, a premier research institution in Malaysia, is dedicated to advancing medical knowledge and improving healthcare outcomes through innovative clinical trials. With a commitment to excellence in research and education, the University collaborates with leading healthcare professionals and researchers to explore cutting-edge treatments and interventions. Its clinical trial programs focus on various health challenges, aiming to translate scientific discoveries into practical applications that benefit diverse populations. By fostering a multidisciplinary approach, the University of Malaya continues to contribute significantly to the global medical research landscape.

Locations

Kuala Lumpur, , Malaysia

Patients applied

0 patients applied

Trial Officials

Lee Fenky, MBBS (IMU)

Principal Investigator

University of Malaya

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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