Effectiveness of Oxymetazoline Added on Nasal Steroid in Rhinitis With Persistent Nasal Obstruction
Launched by MAHIDOL UNIVERSITY · May 1, 2013
Trial Information
Current as of April 30, 2025
Completed
Keywords
ClinConnect Summary
All participants will continue medications for 4 weeks, then stop using interventional medication and still take INS (2 puffs in each nostril twice daily) and OAH (1 tablet once daily) for 2 more weeks. Then, all participants will come for the last visit to see whether rebound nasal symptoms occur. Participants will be asked to record nasal symptom diary card, and nasal peak inspiratory flow. Rhinoconjunctivitis Quality of life Questionnaire (Rcq) will be recorded during visit.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Patient 18 years of age or greater
- • Diagnosis with allergic or nonallergic rhinitis with persistent nasal obstruction
- • Being treated with intranasal steroid and oral antihistamine
- Exclusion Criteria:
- • Underlying disease of hypertension
- • Use oral or nasal decongestant 7 days prior to entering the study
- • Nasal polyp or significant deviated nasal septum
- • Respiratory tract infection 14 days prior to entering the study
About Mahidol University
Mahidol University, a premier institution in Thailand, is dedicated to advancing healthcare through innovative research and education. As a leading sponsor of clinical trials, the university leverages its extensive expertise in medical and health sciences to facilitate rigorous scientific investigations aimed at improving patient care and public health outcomes. With a commitment to ethical practices and collaboration, Mahidol University fosters multidisciplinary approaches, engaging a diverse array of researchers and healthcare professionals to drive meaningful advancements in clinical research.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Bangkok, , Thailand
Patients applied
Trial Officials
Torpong Thongngarm, M.D.
Principal Investigator
Mahidol University
Panitan Pradubpongsa, M.D.
Study Chair
Mahidol University
Paraya Assanasen, M.D.
Study Chair
Mahidol University
Pongsakorn Tantilipikorn, M.D.
Study Chair
Mahidol University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials