A Study to Assess if Scratching the Lining of the Womb Prior to IVF Treatment Increases the Chances of Pregnancy
Launched by NOTTINGHAM UNIVERSITY HOSPITALS NHS TRUST · Jun 18, 2013
Trial Information
Current as of May 30, 2025
Completed
Keywords
ClinConnect Summary
Following consent, participants will be randomised to one of the two trial interventions (endometrial biopsy, or ultrasound scan only = no intervention) by a member of the research team. The procedures will be scheduled for luteinising hormone (LH) day +7 to +9 of the menstrual cycle directly preceding commencement of down-regulation medications. A urine pregnancy test will be performed before the studied procedure. Just prior to the biopsy and directly following it, a transvaginal ultrasound scan will be performed to assess the length of the uterine cavity and endometrial parameters, inclu...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Women with history of primary or secondary infertility undergoing fresh IVF/ ICSI treatment or frozen embryo replacement cycle
- • Age \<49
- Exclusion Criteria:
- • Non- ovulatory cycles
- • Absent uterus
- • Uterine instrumentation within previous 3 menstrual cycles
- • Women in the oocyte donation program
About Nottingham University Hospitals Nhs Trust
Nottingham University Hospitals NHS Trust is a leading healthcare provider in the UK, dedicated to delivering high-quality patient care and advancing medical research. Comprising two major hospitals, Queen's Medical Centre and Nottingham City Hospital, the Trust is at the forefront of clinical innovation and education. With a strong emphasis on translational research, Nottingham University Hospitals NHS Trust actively sponsors clinical trials aimed at improving treatment outcomes and understanding various health conditions. The Trust collaborates with academic institutions, healthcare professionals, and industry partners to foster a robust research environment that enhances clinical practice and contributes to evidence-based medicine.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Nottingham, Nottinghamshire, United Kingdom
Patients applied
Trial Officials
Nick Raine-Fenning, PhD
Study Chair
University of Nottingham
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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