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Search / Trial NCT01918163

Anti-oxidative Influence From Pomegranate Tablets on Male Sperm Quality in Couples Undergo Infertility Treatments Due to Male Infertility.

Launched by HILLEL YAFFE MEDICAL CENTER · Aug 6, 2013

Trial Information

Current as of June 10, 2025

Unknown status

Keywords

Pomegranate Pills, Male Infertility, Pregnancy Rate, Semen Analysis, Ros, Oxidative Stress

ClinConnect Summary

Pomegranate contains a high concentration of vitamins ( C, B1, B2, B3, B5), potassium, Magnesium , Zinc and is a good source for polyphenols .Polyphenols molecules have been found to possess antioxidant properties and may effects the expression of different genes . Recent studies indicate that among foods that contain polyphenols, juice extracted from the pomegranate has the highest concentration of measurable polyphenols . Pomegranates have shown inhibitory effect on NF-κB and the MAP kinases JNK and ERK, which are critical steps in the cascade of events leading to inflammatory response. T...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • TMC of less than 5 million spermatogonia in native sperm and morphology less than 4% by Kruger criteria.
  • Exclusion Criteria:
  • sensitivity to Pomegranate

About Hillel Yaffe Medical Center

Hillel Yaffe Medical Center is a leading healthcare institution dedicated to advancing medical research and improving patient care through innovative clinical trials. Located in Hadera, Israel, the center is committed to fostering cutting-edge scientific inquiry and collaboration across various medical disciplines. With a focus on patient safety and ethical standards, Hillel Yaffe Medical Center actively engages in the development of novel therapies and treatment modalities, aiming to enhance health outcomes and contribute to the global medical community. The center prides itself on its multidisciplinary approach, integrating expertise from experienced researchers and clinicians to drive impactful studies that address critical health challenges.

Locations

Hadera, , Israel

Patients applied

0 patients applied

Trial Officials

Einat Shalom-Paz, MD

Principal Investigator

Hillel Yaffe Medical center, IVF unit, Hadera, Israel

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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