Czech Multicentre Research Database of Chronic Obstructive Pulmonary Disease (COPD)
Launched by ZUZANA ZBOŽÍNKOVÁ, M.SC. · Aug 13, 2013
Trial Information
Current as of May 05, 2025
Unknown status
Keywords
ClinConnect Summary
Chronic Obstructive Pulmonary Disease (COPD) is a treatable and preventable clinically heterogeneous syndrome with dominant respiratory symptoms and various systemic consequences. The incidence of COPD is increasing worldwide. In general, COPD is caused by a prolonged inflammatory reaction of a genetically predisposed individual exposed to long-term inhalation of air pollution, harmful particles and gases. This disease has a negative progression in time even after end of exposure. The pulmonary component is associated with expiratory airflow limitation, which is not fully reversible. The ai...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Post-bronchodilator FEV1/VC \< LLN and post-bronchodilator FEV1 ≤ 60% of the predicted value (VC - Vital Capacity, LLN - Lower Limit of Normal)
- • Definite clinical diagnosis of COPD (can be overlaps: COPD + asthma / COPD + bronchiectasis)
- • Stable course of COPD (≥ 8 weeks free of acute exacerbations and/or free of any acute conditions)
- • Informed consent
- Exclusion Criteria:
- • "Pure" bronchial asthma without COPD
- • "Pure" bronchiectasis without COPD
- • Cystic fibrosis
- • End-stage of COPD
- • Non-curable malignancy
- • Total non-compliance
- • Immobility
About Zuzana Zbožínková, M.Sc.
Zuzana Zbožínková, M.Sc., is a dedicated clinical trial sponsor with a strong background in biomedical research and a commitment to advancing healthcare through innovative studies. With a Master's degree in Science, she possesses a robust understanding of clinical methodologies and regulatory requirements, ensuring that trials are conducted with the highest standards of integrity and ethical considerations. Zuzana's leadership in clinical research is characterized by her collaborative approach, fostering partnerships with healthcare professionals and institutions to facilitate the successful development of novel therapies. Her focus on patient-centered outcomes and data-driven decision-making underscores her dedication to improving clinical practices and contributing to the scientific community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Brno, , Czechia
Hradec Kralove, , Czechia
Olomouc, , Czechia
Ostrava, , Czechia
Liberec, , Czechia
Ceské Budějovice, , Czechia
Jihlava, , Czechia
Mlada Boleslav, , Czechia
Plzen, , Czechia
Prague, , Czechia
Prague, , Czechia
Prague, , Czechia
Usti Nad Labem, , Czechia
Zlin, , Czechia
Patients applied
Trial Officials
Vladimir Koblizek, Assoc. Prof. PhD
Principal Investigator
University Hospital Hradec Kralove
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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