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Search / Trial NCT01923753

A Short-term Comparative Study of Aerosure for Airway Clearance in Patients With Cystic Fibrosis

Launched by ACTEGY LTD. · Aug 14, 2013

Trial Information

Current as of April 29, 2025

Terminated

Keywords

Cystic Fibrosis Neural Respiratory Drive Airway Clearance Technique Expectoration Positive Expiratory Pressure Device

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • A diagnosis of CF (established by genotype or sweat sodium \>70mmol/l or sweat chloride of \>60 mmol/l
  • Admitted to King's College Hospital within 48 hours of an acute infective pulmonary exacerbation characterised by an increase in respiratory symptoms requiring intravenous antibiotics
  • Exclusion Criteria:
  • Acute respiratory failure
  • Haemodynamic instability (including severe right heart failure with hypotension)
  • Current severe haemoptysis
  • Ineffective cough
  • Rib fractures
  • Pregnancy
  • Current or recent pneumothorax
  • Epilepsy
  • Current pulmonary embolism
  • Oesophageal varices
  • Recent thoracic upper gastro-intestinal tract or facial surgery
  • Active tuberculosis
  • Recent brain, eye, ear, ENT surgery
  • Myocardial infarction
  • Ascending aortic aneurysm
  • Acute diarrhoea
  • Pulmonary embolism
  • Angina
  • Severe hypertension (systolic \>200 mm Hg, diastolic \>120 mm Hg)
  • Confusion/dementia
  • Inability to give consent

About Actegy Ltd.

Actegy Ltd. is a pioneering clinical trial sponsor dedicated to advancing innovative healthcare solutions through rigorous research and development. With a focus on medical technologies and therapeutic interventions, Actegy leverages cutting-edge methodologies to design and conduct clinical trials that prioritize patient safety and efficacy. The company collaborates with a network of healthcare professionals and institutions to facilitate the development of products that enhance patient outcomes and improve quality of life. Committed to ethical standards and regulatory compliance, Actegy Ltd. strives to drive scientific progress and contribute to the future of medicine.

Locations

London, , United Kingdom

Patients applied

0 patients applied

Trial Officials

John Moxham, MD

Principal Investigator

King's College Hospital NHS Trust

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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