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Search / Trial NCT01930396

Use of Tinzaparin for Anticoagulation in Hemodialysis

Launched by CHRISTINE RIBIC · Aug 27, 2013

Trial Information

Current as of May 18, 2025

Completed

Keywords

Hemodialysis Anticoagulation Tinzaparin Unfractionated Heparin Randomized Controlled Trial

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>= 18 years
  • End stage renal disease maintained on outpatient hemodialysis for \>= 3 months
  • Frequency of hemodialysis: 3 times per week
  • Anticoagulation with an unfractionated heparin protocol for at least 4 weeks
  • Patient or legal guardian able to provide written consent
  • Baseline INR \<= 1.3
  • Baseline platelet count \>= 80,000 x 10\^9/L
  • Exclusion Criteria:
  • Therapeutic systemic anticoagulation
  • Clinically apparent bleeding in the last 2 months
  • High risk of bleeding
  • Planned major surgery in the next 4 months
  • Major surgery in the past 48 hours
  • Pregnant or lactating
  • Child bearing potential
  • Allergy/intolerance to heparin or history of heparin induced thrombocytopenia
  • Current participation in a related randomized drug trial

About Christine Ribic

Christine Ribic is a dedicated clinical trial sponsor committed to advancing medical research and improving patient outcomes through innovative trial design and execution. With a strong focus on oncology and personalized medicine, she leads a team that collaborates with leading healthcare institutions and researchers to ensure rigorous adherence to regulatory standards and ethical practices. Christine Ribic's expertise in trial management and her passion for patient-centric approaches drive the development of novel therapies, ultimately aiming to enhance treatment options and quality of life for patients facing complex health challenges.

Locations

Hamilton, Ontario, Canada

Patients applied

0 patients applied

Trial Officials

Dr. Christine M Ribic, MD, MSc

Principal Investigator

St. Joseph's Healthcare Hamilton/McMaster University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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