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Search / Trial NCT01932229

An Open Label Study of BIBW 2992/Afatinib in Advanced Non-Small Cell Lung Cancer Patients Pre-treated With Erlotinib or Gefitinib

Launched by SHEBA MEDICAL CENTER · Aug 29, 2013

Trial Information

Current as of May 23, 2025

Unknown status

Keywords

Advanced Nsclc Egfr Mutation Tk Is Tyrosine Kinase Inhibitors

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Advanced NSCLC
  • EGFR mutation or six months or longer benefit from EGFR TKIs
  • Disease progression on chemotherapy, or inability to receive chemotherapy for medical reasons.
  • Disease progression on EGFR TKI, or the presence of an EGFR mutation that does predicts for poor response to first generation EGFR TKIs.
  • Exclusion Criteria:
  • Inability to take oral drugs

About Sheba Medical Center

Sheba Medical Center, located in Israel, is a leading academic medical institution renowned for its commitment to advancing healthcare through innovative research and clinical excellence. As a prominent clinical trial sponsor, Sheba Medical Center leverages its multidisciplinary expertise and state-of-the-art facilities to conduct rigorous clinical studies aimed at improving patient outcomes and developing novel therapeutic interventions. The center's collaborative environment fosters partnerships with global research organizations, enhancing its ability to contribute to the scientific community and drive medical advancements across various fields. With a strong focus on patient safety and ethical standards, Sheba Medical Center is dedicated to translating research findings into practical applications that benefit patients worldwide.

Locations

Ramat Gat, , Israel

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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