Efficacy and Safety of Multisite Cardiac Resynchronization Therapy

Launched by BARZILAI MEDICAL CENTER · Oct 16, 2013

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Eligibility criteria

• Inclusion Criteria:
• • 1. Patients with severe LV dysfunction, severe heart failure (NYHA FC III-IV and at least one hospitalization for congestive heart failure in the past 3 months before inclusion) on optimal medical treatment and that have narrow complex QRS or RBBB. These patients have an indication for ICD implantation.
• • 2. Patients with conventional indications for CRTD implantation and EF\<25%, QRS\>150ms and severe heart failure (NYHA FC\>III).
• • 3. Patients with an indication for pacemaker implantation and an expected high rate of pacing (complete AV block or prior to AVN ablation) and a wish to avoid RV pacing (example: severe TR).
• • 4. Patients with refractory ventricular tachycardia and severe LV dysfunction (EF\<35%) that continue to have VT episodes despite antiarrhythmic drugs and despite recurrent VT ablations. Those patients have indication for ICD.
• • 5. Patients with conventional indications for CRT but during implantation the anatomy is such that the site of implantation is not optimal (QRS\>200ms). In these cases we will add an electrode in the opposite branch of the coronary sinus.
• Exclusion Criteria:
• • Pregnancy
• • Patients included in another study
• • Patients that have other solutions that could avoid implantation (medications, ablation, etc