Minimal Invasive Rehabilitation of Tooth Loss in the Posterior Segment (MIZE-S)

Launched by UNIVERSITY HOSPITAL HEIDELBERG · Nov 22, 2013

Keywords

ClinConnect Summary

The MIZE-S clinical trial is exploring a new way to help people who have lost teeth in the back of their mouths. Traditional treatments, like implant-supported crowns and conventional bridges, can sometimes be difficult due to health issues or costs. This study specifically looks at a less invasive option called resin-bonded bridges, which require little or no alteration of the surrounding teeth. Researchers want to compare two different designs of these all-ceramic bridges to see if they perform similarly in real-life situations.

To be eligible for this study, participants should be between 65 and 75 years old and have missing teeth in certain areas (like the second premolar or molars). They need to be regular patients at the University Hospital of Heidelberg and willing to attend follow-up appointments. The study excludes individuals who are pregnant, have certain health problems, or have severe dental issues. Participants can expect to contribute to the understanding of these new dental options, helping to improve treatment for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • missing second premolar, or first molar, or second molar
• • regular patient of the department of prosthodontics of the university hospital of heidelberg
• • willingness to return for recall examinations on a regular basis
• • written informed consent
• • abutment teeth are vital or sufficiently endodontically treated
• • abutment teeth are periodontally stable
• • abutment teeth have only little or no defects of the hardsubstances
• Exclusion Criteria:
• • Pregnancy or breastfeeding
• • medically compromised condition not allowing for standard dental treatment
• • Patient is not able to give written informed consent
• • alcohol or drug abuse
• • positive bruxism and parafunctions questionaire
• • Bite-Strip \> 2
• • Attrition Score \> 3
• • deep bite (Angle class II/2)
• • abutment tooth height \< 4mm
• • missing canine or first premolar
• • gap size \> 18 mm
• • untreated symptomatic periodontal or endodontic lesions
• • abutment tooth mobility \> grade I
• • known allergies to materials used in this study
• • poor dental hygiene
• • planned change of residency