Evaluation of Choroidal Thickness During Pregnancy Using Enhanced Depth Imaging Optical Coherence Tomography

Launched by GAIA HOSPITAL · Dec 30, 2013

Keywords

ClinConnect Summary

Pregnant women in the last trimester and age-matched healthy controls have an Optical Coherence Tomography (OCT) image taken on the OCT Spectralis® device.

A map of the choroid in the macular area is constructed automatically. Choroidal thickness and volume are calculated for the 9 subfields defined by the Early Treatment Diabetic Retinopathy Study (ETDRS).

A comparative analysis between the two groups will be performed. As a secondary outcome measure, the change in choroidal thickness of the pregnant group of women will be assessed at 6 months postpartum by comparison to the 3rd trimeste...

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• Pregnant women:
• • uncomplicated pregnancy in the third trimester (from 28 weeks of gestation)
• For both groups:
• • no systemic or ocular disease
• • absence of systemic medication other than prenatal vitamins
• • no smoking habits
• • emmetropia or a small refractive error (spherical equivalent \<1.5 diopters)
• Exclusion Criteria:
• • any of the above