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Search / Trial NCT02048709

Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors

Launched by GENENTECH, INC. · Jan 27, 2014

Trial Information

Current as of May 20, 2025

Completed

Keywords

ClinConnect Summary

No description provided

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Histologically or cytologically confirmed solid tumor that is relapsed/refractory to standard therapies or for which no approved or curative therapy exists
  • Age \> or = 18
  • Eastern Cooperative Oncology Group (ECOG) performance status \< 2
  • Life expectancy \> or = 12 weeks
  • Adequate hematologic and organ function before initiation of GDC-0919
  • For some patients only: Accessible lesions amenable to paired fresh tumor biopsies
  • Exclusion Criteria:
  • Some prior cancer immunotherapies
  • Untreated brain metastases
  • Active or history of autoimmune disease

About Genentech, Inc.

Genentech, Inc. is a leading biotechnology company and a member of the Roche Group, dedicated to transforming the lives of patients with serious medical conditions through innovative therapies. Established in 1976, Genentech is recognized for its pioneering research in biologics and for developing groundbreaking treatments in areas such as oncology, immunology, and neuroscience. With a commitment to scientific excellence and patient-centered care, the company leverages cutting-edge technology and collaborative partnerships to advance drug discovery and development. Genentech's robust pipeline and focus on personalized medicine underscore its mission to address unmet medical needs and improve health outcomes globally.

Locations

Augusta, Georgia, United States

Patients applied

0 patients applied

Trial Officials

Clinical Trials

Study Director

Hoffmann-La Roche

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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