Comparing G6PD Tests Using Capillary Blood Versus Venous Blood
Launched by PATH · Feb 19, 2014
Trial Information
Current as of May 08, 2025
Completed
Keywords
ClinConnect Summary
In this study we propose to determine the correlation in glucose-6 phosphate dehydrogenase enzyme activity in capillary blood obtained from a finger stick versus a venous blood specimen. We will also compare results of different G6PD tests with known G6PD genetic profiles. The results of the study will inform design of future G6PD diagnostic development \& evaluations. This research will be conducted in MaeSot Thailand, where G6PD deficiency has a high prevalence. Study participants will be recruited into three groups of 50 volunteers per group: 50 G6PD-deficient individuals, 50 G6PD-normal...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Previous G6PD test at SMRU clinic
- • Patient willing to participate and sign informed consent form
- • Patient willing to allow donated sample to be used in future research
- • Subjects 18 years of age or older
- Exclusion Criteria:
- • patients with severe malaria or other severe illness
- • Patients who received a blood transfusion in the last 3 months
- • Patients who received primaquine in the past 1 month (this is to ensure that previous characterization of phenotype in the healthy subject has not been influenced by a recent hemolytic reaction)
About Path
Path is a leading global non-profit organization dedicated to improving public health by developing and implementing innovative solutions to health challenges. With a focus on enhancing healthcare access and equity, Path collaborates with governments, NGOs, and private sector partners to design and deliver effective interventions and technologies. The organization specializes in areas such as infectious diseases, maternal and child health, and vaccine development, leveraging research and data to inform evidence-based practices. Through its commitment to advancing health systems and empowering communities, Path strives to create sustainable health improvements for populations worldwide.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Mae Sot, , Thailand
Patients applied
Trial Officials
Francois Nosten, MD/PhD
Principal Investigator
Shoklo Malaria Research Unit, Mahidol Oxford Research unit
Gonzalo Domingo, PhD
Study Chair
PATH
Germana Bancone, PhD
Study Chair
Shoklo Malaria Research Unit, Mahidol Oxford Research unit
Sarah McGray, MPH
Study Chair
PATH
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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