Hyaluronic Acid for Hypofractionated Prostate Radiotherapy

Launched by HOSPICES CIVILS DE LYON · Jun 13, 2014

Keywords

ClinConnect Summary

No description provided

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • age superior or equal to 18 years and inferior to 80 years.
• • patient with a low- to intermediate-risk prostate cancer, according to D'Amico classification, for an exclusive irradiation.
• • prostate cancer histologically proven.
• • life expectancy superior to 10 years.
• • Karnofsky performance status ≥ 60% (performance status ECOG 0-2).
• • the patient has to be the beneficiary of a social security system or other insurance (order n° 2006-477 from April 26th 2006).
• • the signed consent form.
• Exclusion Criteria:
• • age inferior to 18 years and ≥ 80 years;
• • history of rectal surgery;
• • patient who can't cooperate during the treatment;
• • history of pelvic irradiation;
• • history of inflammatory bowel disorder such as ulcerative colitis or the Crohn's disease;
• • other current neoplasia or history of neoplasia dating from less than 5 months, excepting basal-cell carcinomas;
• • patients treated with anti-neoplastic or anti-angiogenic or with other treatments used in rheumatology and which may include methotrexate (in order not to have a radiosensitizing effect);
• • patients receiving anticoagulant treatment or PLAVIX;
• • other undergoing study that may interfere with the present study;
• • patient under legal protection measure.