EEG Characteristics in Youth POTS and/or Syncope

Launched by NATIONWIDE CHILDREN'S HOSPITAL · Jun 17, 2014

Keywords

ClinConnect Summary

All POTS and syncope patients referred to Nationwide Children's Hospital (Columbus, OH) and meeting study eligibility criteria will be asked to participate. Consent and assent will be obtained per IRB guidelines. Consenting patients will undergo head-upright tilt (HUT) testing with video EEG and continuous sweat monitoring.

Prior to testing all medicines that can affect orthostatic tolerance will be held a minimum of 5 half-lives. Caffeine will be held for a minimum of 24 hours. Urinalysis (for urine specific gravity) and pregnancy testing (for female patients of child-bearing age) will be...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients aged 9-21 years
• • Referred to the neurology POTS and Syncope clinic at Nationwide Children's Hospital for clinical tilt table testing
• • Has prior diagnosis or signs/symptoms of POTS (with or without syncope) or syncope (without POTS)
• Exclusion Criteria:
• • Cognitive, somatic or psychiatric illness that precludes tilt table testing, prolonged standing, or EEG lead placement
• • Known seizure disorder
• • Scalp or skull defect that could affect EEG amplitudes
• • Pregnancy
• • Non-English speaking