To Determine the Effect of Honey Enema in the Treatment of Patients With Acute Pouchitis
Launched by DR. CARL J BROWN · Jul 23, 2014
Trial Information
Current as of May 17, 2025
Completed
Keywords
ClinConnect Summary
Pouchitis is the most common long-term complication of ileal pouch-anal anastomosis (IPAA) in ulcerative colitis (UC). Pouchitis is defined as a clinical syndrome of watery, frequent, at times bloody stool accompanied by urgency, incontinence, abdominal cramps, malaise, and fever. The PDAI (Pouchitis Disease Activity Index) provides a standardized definition of pouchitis based on clinical, endoscopic, and histological markers. Pouchitis is defined as a score ≥ 7 and remission as a score \< 7. Recently, the modified Pouchitis Disease Activity Index has been used to omit biopsy and histology ...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • have given written informed consent
- • have been diagnosed with ulcerative colitis
- • have had total colectomy and ileal pouch anal anastomosis before
- • have presented with signs and symptoms of pouchitis within the last two months of signing the informed consent
- • PDAI of greater than or equal to 7
- Exclusion Criteria:
- • patients who are unable to perform enema by themselves
- • patients with an allergy to honey
About Dr. Carl J Brown
Dr. Carl J. Brown is a distinguished clinical trial sponsor with extensive expertise in advancing medical research and therapeutic innovations. With a focus on enhancing patient outcomes, Dr. Brown leads initiatives that rigorously evaluate novel treatments across various medical disciplines. His commitment to ethical research practices and patient safety ensures that clinical trials are conducted with the highest standards of scientific integrity. Dr. Brown's collaborative approach fosters partnerships with leading healthcare institutions and regulatory bodies, driving the successful development of cutting-edge therapies that address unmet medical needs.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Vancouver, British Columbia, Canada
Patients applied
Trial Officials
Carl Brown
Principal Investigator
Saint Paul's Hospital
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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