Effect of an Eccentric Exercise Program on Quality of Life and Function in People With Chronic Heart Failure.
Launched by LA TROBE UNIVERSITY · Aug 21, 2014
Trial Information
Current as of June 12, 2025
Completed
Keywords
ClinConnect Summary
BACKGROUND A systematic literature review we conducted yielded two trials investigating eccentric exercise in patients with coronary artery disease and two trials in the chronic heart failure population. Eccentric exercise was reported to be a safe form of exercise for coronary patients, causing minimal heart and breathing stress and being perceived as "fairly light" exertion. Eccentric exercise, when compared with concentric exercise (shortening contractions) resulted in comparable improvements in muscle strength and walking distance, often with reduced oxygen usage.
With no increase in n...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • aged \> 18 years
- • a clinical diagnosis of heart failure either systolic or diastolic on transthoracic echocardiogram
- • mild to moderate heart failure
- • medically stable heart failure
- • have received approval when assessed by the group physiotherapist to participate in the exercise program as is usual practice. Where concerns arise during assessment, clearance will be sought from the treating cardiologist.
- Exclusion Criteria:
- • hospitalisation for a CHF exacerbation within the previous month
- • severe heart failure classified as level four on the New York heart association classification (short of breath at rest)
- • unstable medical condition such as uncontrolled angina, diabetes or hypertension
- • dementia or a psychological disorder that would interfere with participation in group exercise
- • participation in a cardiac or heart failure rehabilitation program in the prior six months
- • contraindications to exercise (ie aneurysm, valvular disease)
- • the presence of any pre-existing neurological or musculoskeletal condition, for example stroke, that on assessment is deemed to interfere with exercise participation.
About La Trobe University
La Trobe University is a leading educational institution based in Australia, renowned for its commitment to research excellence and innovation in health sciences. As a clinical trial sponsor, La Trobe University leverages its extensive academic resources and multidisciplinary expertise to advance medical research and improve patient outcomes. The university fosters collaboration between researchers, healthcare professionals, and industry partners, ensuring that clinical trials are conducted with the highest standards of integrity and scientific rigor. Through its dedication to ethical practices and community engagement, La Trobe University aims to contribute significantly to the advancement of medical knowledge and the development of effective therapies.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Epping, Victoria, Australia
Patients applied
Trial Officials
Rachel E Ellis
Principal Investigator
Northern Hospital, Australia
Kwang Lim
Principal Investigator
Melbourne Health
Karen J Dodd
Principal Investigator
Victoria University
Anne E Holland
Principal Investigator
La Trobe University
Nora Shields
Principal Investigator
La Trobe University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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