Effects of Embryogen in RIF Patients
Launched by VIETNAM NATIONAL UNIVERSITY · Sep 23, 2014
Trial Information
Current as of May 14, 2025
Completed
Keywords
ClinConnect Summary
60 patients with repeated implantation failure were involved.
RIF was defined as patients failed to conceive (beta-hCG \< 5 mIU/mL) after at least 03 embryo transfers (fresh and frozen) with 06 top quality embryos or more.
Ovarian stimulation was performed using GnRH antagonist protocol. All matured oocytes were inseminated by ICSI. Injected oocytes were cultured in medium supplemented with 2ng/ml of GM-CSF (Embryogen, Origio) until day of transfer. Embryo evaluation was performed at fixed time points of 18 and 44 hour after fertilization. Embryo transfer was performed 2 days after ovum re...
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Normal ovarian reserve (AMH \> 1.1 ng/ml)
- • Regular menstrual cycle (25 - 34 days)
- • Clear informations about at least 3 latest IVF/ET
- • Fresh embryo transfer in this cycle
- • Endometrial thickness of 10 mm or more
- Exclusion Criteria:
- • Undergo oocyte donation or in vitro maturation (IVM) cycles
- • Using frozen or surgically retrieved sperm
- • Adenomyosis, Uterine anomaly, uterine fibroid, hydrosalpinges
- • In participation in other studies/interventions
About Vietnam National University
Vietnam National University (VNU) is a leading academic institution dedicated to advancing research and education in Vietnam. As a clinical trial sponsor, VNU leverages its extensive network of interdisciplinary expertise and state-of-the-art facilities to facilitate innovative healthcare solutions and contribute to the global medical community. The university is committed to conducting rigorous clinical research that adheres to the highest ethical standards, aiming to enhance patient care and support evidence-based practices. Through collaboration with healthcare professionals, researchers, and industry partners, VNU plays a pivotal role in addressing pressing health challenges and fostering scientific advancements in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Ho Chi Minh, , Vietnam
Patients applied
Trial Officials
Vinh Q Dang, Dr
Principal Investigator
Research Center for Genetics and Reproductive Health
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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