Long-term Sacral Nerve Stimulation for Irritable Bowel Syndrome.

Launched by UNIVERSITY OF AARHUS · Nov 14, 2014

Keywords

ClinConnect Summary

Twenty two patients with IBS-D or IBS-M according to the ROME III criteria, will be enrolled by invitation in the study.

Having meet inclusion criteria, the patients are first set subsensory for 4 weeks and then randomised to receive either OFF-subsensory or subsensory-OFF stimulation in a 4+4-week period.

During the PNE test the effect of the stimulation is evaluated by specific IBS symptom and quality of life questionnaires (GSRS-IBS and IBS-IS) and bowel habit diaries.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients who are psychologically stable and suitable for intervention and able to provide informed consent
• • Patients who are diagnosed with IBS according to the Rome III criteria and characterised with IBS-D or IBS-M.
• • Patients who have been treated with sacral nerve stimulation for a minimum of 3 years.
• Exclusion Criteria:
• • Other bowel diseases including inflammatory bowel disease
• • Pregnant or breast feeding
• • Patients who are considered unable to follow the planned programme of the study, including mentally illness or physiological instability
• • Patients who are on medication with known influence on gastrointestinal motility including those for thyroid disease, diabetes mellitus, celiac disease and neurological diseases.