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A Follow-net Investigation of a Randomised Study of Cystoscopy and Urethral Dilatation Versus Cystoscopy Alone in Women With Overactive Bladder Syndrome and Impaired Voiding

Launched by MEDWAY NHS FOUNDATION TRUST · Nov 18, 2014

Trial Information

Current as of May 07, 2025

Withdrawn

Keywords

ClinConnect Summary

Urinary incontinences is a highly prevalent and distressing condition which has a significant impact on health related quality of life in millions of women worldwide. Of all women with incontinence, 90% will have overactive bladder symptoms (OAB), and 50% will have detrusor overactivity (DO) on cystometry. The overactive bladder syndrome is defined by the International Continence society as "Urinary urgency, with or without urge incontinence, usually with frequency and nocturia if there is a no infection or proven pathology" (Abrams et al 2002)

Initial management of OAB and DO consists of ...

Gender

FEMALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. Significant Overactive Bladder Symptoms
  • Based on scoring 1 or 2 on the Urgency Perception Scale
  • On the symptoms domain of the KHQ
  • More than 8 voids per day on frequency volume chart +/- 2 or more episodes of nocturia
  • 2. Pressure flow studies demonstrate a maximum flow rate of less than 15ml on a minimum voided volume of 200ml with a high or normal detrusor pressure at maximum flow or post-void residual of 200ml or over
  • 3. Patients must be able to give informed consent for the study.
  • Exclusion Criteria:
  • 1. Presence of concurrent urodynamic stress incontinence.
  • 2. Patients with bladder pathology or haematuria of unknown origin.
  • 3. Patients with neurological disorders (as these may affect voiding).
  • 4. Symptomatic pelvic organ prolapse requiring intervention
  • 5. Patients with bladder pathology (including urinary tract infection) or haematuria of unknown origin

About Medway Nhs Foundation Trust

Medway NHS Foundation Trust is a leading healthcare provider in the United Kingdom, dedicated to delivering high-quality patient care and advancing medical research through clinical trials. With a strong emphasis on innovation and collaboration, the Trust actively participates in various studies aimed at improving treatment outcomes and enhancing patient experiences. Its multidisciplinary team of healthcare professionals is committed to adhering to rigorous ethical standards and regulatory requirements, ensuring that all clinical trials are conducted with the utmost integrity and patient safety in mind. Through its research initiatives, Medway NHS Foundation Trust strives to contribute to the advancement of medical science and the development of new therapeutic options.

Locations

Patients applied

0 patients applied

Trial Officials

Jonathan RA Duckett, FRCOG, MBChB

Principal Investigator

Medway Maritime Hospital

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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