Transcutaneous-Arterial Carbon Dioxide and Microcirculatory Dysfunction
Launched by UNIVERSITY OF VIRGINIA · Dec 23, 2014
Trial Information
Current as of April 28, 2025
Withdrawn
Keywords
ClinConnect Summary
There is increasing evidence that despite resuscitation and normalization of macrohemodynamic parameters (blood pressure and cardiac output) significant dysfunction of the microcirculation may persist.1, 2 There is also a positive correlation between the severity of microcirculatory dysfunction and outcome in patients with septic shock. In contrast, early improvements in microcirculatory perfusion in response to macrohemodynamic goal directed therapy is associated with an improvement in organ function.3 Monitoring the microcirculation is challenging. The monitoring window (e.g. the sublingu...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • 1. Age \> 18 years
- • 2. Elective cardiac surgery
- • 3. Must be able to read and speak English
- Exclusion Criteria:
- • 1. Subjects unable/unwilling to give informed consent
- • 2. Emergency surgery
- • 3. Age \< 18 years
- • 4. Pregnant females-self reported
- • 5. Prisoners
About University Of Virginia
The University of Virginia (UVA) is a prestigious academic institution renowned for its commitment to advancing medical research and improving patient care through innovative clinical trials. With a focus on interdisciplinary collaboration, UVA leverages its extensive resources and expertise in various fields, including medicine, engineering, and public health, to drive cutting-edge studies that address pressing health challenges. The university's clinical trial programs aim to translate scientific discoveries into effective treatments, ensuring the highest standards of ethical practice and participant safety. Through its strong emphasis on community engagement and education, UVA fosters a culture of research that not only contributes to the scientific community but also enhances the well-being of the populations it serves.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Trial Officials
Bhiken I Naik, M.B.B.Ch
Principal Investigator
University of Virginia
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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