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Search / Trial NCT02332538

HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH

Launched by MANSOURA UNIVERSITY · Jan 6, 2015

Trial Information

Current as of May 10, 2025

Completed

Keywords

Laser Prostate Bipolar Hyperplasia Vaporization

ClinConnect Summary

With a growing body of knowledge on the promising advancements and recent clinical data of the third generations of the Greenlight XPS, it seems to be a real contender in the world of MIS. Contenders of Greenlight laser technology includes bipolar as well as Holmium laser technology.

In this study the investigators planned to test the Greenlight (532-nm) laser Photoselective Vapo-Enucleation of the Prostate (PVEP) using (XPS) 180W system compared to bipolar transurethral resection of the prostate (TURis) and Holmium Laser Enucleation of the Prostate (HOLEP) in reduction of LUTS secondary t...

Gender

MALE

Eligibility criteria

  • Inclusion Criteria:
  • 1. Patients' age ≥50 years
  • 2. LUTS secondary to BOO due to BPH who failed medical treatment
  • 3. International prostate symptom scores 8 (IPSS) \>15 and bother score 8 (QOL) ≥ 3 (according to IPSS question 8)
  • 4. Peak urinary flow rate (Qmax) \<15 ml/sec with at least 125 ml voided volume or Patients with acute urine retention secondary to BPH who failed trial of voiding on medical treatment.
  • 5. ASA (American society of anaesthesiologists) score ≤3.
  • 6. TRUS prostate size (\>/=80ml)
  • Exclusion Criteria:
  • 1. Patient with neurological disorder which might affect bladder function as cerebrovascular stroke, Parkinson disease
  • 2. Active urinary tract infection,
  • 3. Presence of active bladder cancer (within the last 2 years)
  • 4. Known prostate cancer patients will be excluded preoperatively on the basis of digital rectal examination, prostate specific antigen level, and TRUS imaging followed by prostate biopsies if necessary.

About Mansoura University

Mansoura University is a prestigious academic institution located in Egypt, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, it leverages its extensive resources and expertise in various fields of healthcare to facilitate innovative research initiatives aimed at improving patient outcomes. The university collaborates with a network of healthcare professionals and researchers to conduct high-quality clinical trials, focusing on addressing critical health challenges through rigorous scientific methodologies. Its dedication to ethical research practices and adherence to regulatory standards underscores its role as a leader in the medical research community.

Locations

Mansoura, Aldakahlia, Egypt

Patients applied

0 patients applied

Trial Officials

Ahmed M Elshal, MD

Principal Investigator

Mansoura University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported

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