HoLEP vs. Greenlight 532nm-laser PVEP vs. Bipolar TURP in Management of Moderate/ Large BPH
Launched by MANSOURA UNIVERSITY · Jan 6, 2015
Trial Information
Current as of May 10, 2025
Completed
Keywords
ClinConnect Summary
With a growing body of knowledge on the promising advancements and recent clinical data of the third generations of the Greenlight XPS, it seems to be a real contender in the world of MIS. Contenders of Greenlight laser technology includes bipolar as well as Holmium laser technology.
In this study the investigators planned to test the Greenlight (532-nm) laser Photoselective Vapo-Enucleation of the Prostate (PVEP) using (XPS) 180W system compared to bipolar transurethral resection of the prostate (TURis) and Holmium Laser Enucleation of the Prostate (HOLEP) in reduction of LUTS secondary t...
Gender
MALE
Eligibility criteria
- Inclusion Criteria:
- • 1. Patients' age ≥50 years
- • 2. LUTS secondary to BOO due to BPH who failed medical treatment
- • 3. International prostate symptom scores 8 (IPSS) \>15 and bother score 8 (QOL) ≥ 3 (according to IPSS question 8)
- • 4. Peak urinary flow rate (Qmax) \<15 ml/sec with at least 125 ml voided volume or Patients with acute urine retention secondary to BPH who failed trial of voiding on medical treatment.
- • 5. ASA (American society of anaesthesiologists) score ≤3.
- • 6. TRUS prostate size (\>/=80ml)
- Exclusion Criteria:
- • 1. Patient with neurological disorder which might affect bladder function as cerebrovascular stroke, Parkinson disease
- • 2. Active urinary tract infection,
- • 3. Presence of active bladder cancer (within the last 2 years)
- • 4. Known prostate cancer patients will be excluded preoperatively on the basis of digital rectal examination, prostate specific antigen level, and TRUS imaging followed by prostate biopsies if necessary.
About Mansoura University
Mansoura University is a prestigious academic institution located in Egypt, renowned for its commitment to advancing medical research and education. As a clinical trial sponsor, it leverages its extensive resources and expertise in various fields of healthcare to facilitate innovative research initiatives aimed at improving patient outcomes. The university collaborates with a network of healthcare professionals and researchers to conduct high-quality clinical trials, focusing on addressing critical health challenges through rigorous scientific methodologies. Its dedication to ethical research practices and adherence to regulatory standards underscores its role as a leader in the medical research community.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Mansoura, Aldakahlia, Egypt
Patients applied
Trial Officials
Ahmed M Elshal, MD
Principal Investigator
Mansoura University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
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