Cognitive Remediation Therapy in Schizophrenia: Effects on BDNF Levels
Launched by HOSPITAL CLINIC OF BARCELONA · Jan 13, 2015
Trial Information
Current as of May 20, 2025
Completed
Keywords
ClinConnect Summary
Forty patients with schizophrenia disorder and twenty healthy volunteers will be recruited. Patients will be randomly allocated either the experimental group, undergoing an individual CRT for 40 hours during 16 weeks, or the control group following a psycho-educational intervention without any neurocognitive work, both lasting the same amount of hours and period of time. Blood samples will be obtained from participants in four moments: before treatment, at week 4, at week 16, and at 32 week follow-up. In addition, repeated measurements will be obtained with a neurocognitive battery based on...
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Diagnosis of schizophrenia according to DSM-IV-TR and confirmed by the semi-structured interview (SCID) for the axis 1.
- • Presence of cognitive deficit confirmed by the neuropsychological battery
- • Stable symptomatology at least during the last six months and the estimation of not modifying pharmacological antipsychotic treatment.
- Exclusion Criteria:
- • Presence of organic-cerebral affectation due to neurological or traumatic conditions
- • Abuse of psychotropic substances
- • Presence of other psychiatric symptomatology
About Hospital Clinic Of Barcelona
The Hospital Clinic of Barcelona is a leading academic medical center renowned for its commitment to advancing healthcare through innovative research and clinical trials. With a strong emphasis on multidisciplinary collaboration, the hospital integrates cutting-edge medical practices with rigorous scientific inquiry to enhance patient outcomes. As a prominent sponsor of clinical trials, the Hospital Clinic of Barcelona is dedicated to exploring new therapies and treatment modalities across various medical fields, fostering a culture of excellence in clinical research that ultimately aims to improve the quality of care for patients locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Barcelona, , Spain
Patients applied
Trial Officials
Rafael Penadés, Ph.D.
Principal Investigator
Hospital Clinic of Barcelona
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported
Similar Trials