Wound Dressings for Pemphigus and Pemphigoid

Launched by FUNDACIÓN NACIONAL PARA LA ENSEÑANZA Y LA INVESTIGACIÓN DE LA DERMATOLOGÍA A.C. · Feb 18, 2015

Keywords

ClinConnect Summary

Pemphigus and pemphigoid are the most frequently autoinmune bullous diseases seen in dermatology. Despite all the treatments that have been studied for the management of bullous skin diseases, there is insufficient information about the best skin dressing or cover that can be used in affected or denuded areas in these conditions.

Therefore we will compare the efficacy of four different covers (gauze with petrolatum , cellulose acetate with petrolatum , pure carboxymethylcellulose with silver and nanocrystalline silver) in providing faster healing and decreasing pain and itch.

Each patient...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Diagnosis of pemphigus vulgaris, pemphigus foliaceus , pemphigus vegetans, paraneoplastic pemphigus or bullous pemphigoid
• • At least four areas of active disease in the trunk or limbs of 8 x 8 cm characterized by denudation, ulceration, scabs or blisters.
• • Capable of being evaluated weekly either as outpatient or hospitalized
• • Actively treated with immunosuppressive or immunomodulatory drugs for pemphigus or pemphigoid control
• • Willing to sign an informed consent
• Exclusion Criteria:
• • Patients with hypersensitivity to any of the components of the skin dressings that will be used.
• • Patients who have participated in any clinical trial in the last 30 days.